Description

6-Chloro-2-Piperazin-1-Yl-Quinoline is a high-purity, synthetically valuable heterocyclic compound featuring a quinoline core substituted with a chloro group and a piperazine moiety. This specific molecular architecture makes it a critical pharmaceutical intermediate and a versatile building block for advanced organic synthesis. It is primarily utilized by research institutions and chemical manufacturers engaged in the development of active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders, infectious diseases, and oncology.
• Agrochemical Research: Serves as a core structure for developing new pesticides, herbicides, and fungicides with specific biological activity.
• Chemical Synthesis Building Block: Used in medicinal chemistry for structure-activity relationship (SAR) studies and the creation of complex molecular libraries.
• Ligand and Catalyst Development: The piperazine nitrogen atoms can act as coordination sites for metal ions, useful in creating catalysts or metal-organic frameworks (MOFs).
• Material Science Research: Investigated as a component for organic electronic materials due to its conjugated quinoline system.

Basic Information

Product Name	6-Chloro-2-Piperazin-1-Yl-Quinoline
CAS No.	78060-46-5
Molecular Formula	C₁₃H₁₄ClN₃
Molecular Weight	247.72 g/mol
Synonyms	6-Chloro-2-(1-piperazinyl)quinoline; 2-(Piperazin-1-yl)-6-chloroquinoline; 6-Chloro-2-piperazinylquinoline; Quinoline, 6-chloro-2-(1-piperazinyl)-; 78060-46-5; 6-Chloro-2-(piperazin-1-yl)quinoline; 6-Chloro-2-(1-piperazinyl)chinolin
EINECS	Contact for details

Quality Control

Our 6-Chloro-2-Piperazin-1-Yl-Quinoline is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and synthesis. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.