Description

4,5-Difluoro-2-Nitroaniline is a high-purity fluorinated aromatic amine derivative, serving as a critical building block in advanced organic synthesis. Its value lies in the strategic placement of fluorine and nitro groups on the aniline core, enabling precise molecular modifications for performance-driven applications. This compound is essential for R&D chemists and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug molecules, particularly those requiring fluorinated scaffolds for enhanced metabolic stability and bioavailability.
• Agrochemical Synthesis: Used in the development of new-generation herbicides, pesticides, and fungicides, where the difluoro-nitroaniline structure contributes to specific biological activity.
• Dye and Pigment Manufacturing: Serves as a versatile intermediate for creating specialized azo dyes and organic pigments with unique color properties and lightfastness.
• Material Science Research: Employed in the development of advanced polymers, liquid crystals, and electronic materials where fluorinated aromatic units are required.
• Cross-Coupling Reactions: Acts as a substrate in palladium-catalyzed reactions (e.g., Buchwald-Hartwig amination) for constructing complex nitrogen-containing heterocycles.

Basic Information

Product Name	4,5-Difluoro-2-Nitroaniline
CAS No.	78056-39-0
Molecular Formula	C6H4F2N2O2
Molecular Weight	174.11 g/mol
Synonyms	2-Nitro-4,5-difluoroaniline; 4,5-Difluoro-2-nitrobenzenamine; 1-Amino-4,5-difluoro-2-nitrobenzene; 4,5-Difluoro-o-nitroaniline; Benzenamine, 4,5-difluoro-2-nitro-; 78056-39-0; 4,5-DFNA
EINECS	Contact for details

Quality Control

Our 4,5-Difluoro-2-Nitroaniline is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and consistent performance. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, handling and transfer should be minimized under direct light exposure.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.