Description

(3-Chlorobenzyl)Phosphonic Acid Diethyl Ester is a versatile organophosphorus compound that serves as a critical synthetic intermediate. Its value lies in its ability to act as a phosphonate building block, enabling the introduction of a functionalized benzyl group into more complex molecular architectures. This product is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, where it is used in the development of active ingredients and specialty chemicals.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of novel drug candidates, particularly those targeting enzyme inhibition.
• Agrochemical Synthesis: Building block for creating advanced herbicides, fungicides, and plant growth regulators.
• Ligand and Catalyst Development: Used to prepare phosphonate-based ligands for metal catalysis and coordination chemistry.
• Material Science Research: Intermediate for synthesizing flame retardants, plasticizers, and other functional polymers.
• Organic Synthesis: Employed in Horner-Wadsworth-Emmons (HWE) olefination reactions to construct carbon-carbon double bonds.
• Chemical Biology Probes: Useful for developing activity-based probes and other tools for biochemical research.

Basic Information

Product Name	(3-Chlorobenzyl)Phosphonic Acid Diethyl Ester
CAS No.	78055-64-8
Molecular Formula	C11H16ClO3P
Molecular Weight	262.67 g/mol
Synonyms	Diethyl (3-Chlorobenzyl)phosphonate; (3-Chlorobenzyl)phosphonic Acid Diethyl Ester; Diethyl (3-Chlorophenylmethyl)phosphonate; Phosphonic Acid, P-[(3-Chlorophenyl)methyl]-, Diethyl Ester; Diethyl (m-Chlorobenzyl)phosphonate; m-Chlorobenzylphosphonic Acid Diethyl Ester; 3-Chlorobenzylphosphonic Acid Diethyl Ester; Diethyl 3-Chlorobenzylphosphonate
EINECS	Contact for details

Quality Control

Our (3-Chlorobenzyl)Phosphonic Acid Diethyl Ester is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing specifications and results are provided and available upon request, supporting your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area away from incompatible materials such as strong bases. Recommended storage temperature is 2-8°C for long-term stability. Keep container tightly sealed when not in use to minimize moisture absorption.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Density (at 20°C)	~1.20 g/cm³

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.