Description

3-Quinolinecarboxylic Acid, 1,4,5,6,7,8-Hexahydro-5-Oxo-4-(2-(Trifluoromethyl)Phenyl)-2,7,7-Trimethyl-, Ethyl Ester is a sophisticated, multi-functional heterocyclic compound featuring a fused quinoline core and a trifluoromethylphenyl substituent. This molecular architecture makes it a valuable advanced pharmaceutical intermediate and a versatile building block for organic synthesis. It is primarily sought after by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, or infectious diseases.
• Agrochemical Research: Serves as a core structure for developing new herbicides, fungicides, or insecticides, leveraging the biological activity of the quinoline moiety.
• Organic Synthesis Building Block: Used in medicinal and combinatorial chemistry for constructing diverse chemical libraries due to its multiple reactive sites and the presence of the trifluoromethyl group, which is known to enhance metabolic stability and lipophilicity.
• Material Science Applications: Potential use in the development of organic semiconductors, light-emitting materials, or specialty polymers where its conjugated system can be utilized.
• Chemical Reference Standard: Supplied to analytical laboratories and quality control departments for method development, validation, and as a certified reference material.

Basic Information

Product Name	3-Quinolinecarboxylic Acid, 1,4,5,6,7,8-Hexahydro-5-Oxo-4-(2-(Trifluoromethyl)Phenyl)-2,7,7-Trimethyl-, Ethyl Ester
CAS No.	78050-80-3
Molecular Formula	C22H24F3NO3
Molecular Weight	407.43 g/mol
Synonyms	Ethyl 1,4,5,6,7,8-hexahydro-5-oxo-4-[2-(trifluoromethyl)phenyl]-2,7,7-trimethyl-3-quinolinecarboxylate; 4-(2-Trifluoromethylphenyl)-1,4,5,6,7,8-hexahydro-5-oxo-2,7,7-trimethylquinoline-3-carboxylic acid ethyl ester; 1,4,5,6,7,8-Hexahydro-5-oxo-4-(2-trifluoromethylphenyl)-2,7,7-trimethylquinoline-3-carboxylic acid ethyl ester; Ethyl 4-(2-trifluoromethylphenyl)-1,4,5,6,7,8-hexahydro-5-oxo-2,7,7-trimethyl-3-quinolinecarboxylate; Ethyl 5-oxo-4-(2-(trifluoromethyl)phenyl)-1,4,5,6,7,8-hexahydro-2,7,7-trimethylquinoline-3-carboxylate; CAS 78050-80-3.
EINECS	Contact for details

Quality Control

Our production of 3-Quinolinecarboxylic Acid, 1,4,5,6,7,8-Hexahydro-5-Oxo-4-(2-(Trifluoromethyl)Phenyl)-2,7,7-Trimethyl-, Ethyl Ester adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure high purity and structural identity. We provide detailed Certificates of Analysis (COA) with each shipment, documenting all critical quality attributes. Our commitment to cGMP and ISO 9001 standards ensures traceability, consistency, and reliability for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents, strong acids, and strong bases. For long-term storage, consider an inert atmosphere to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.