Description

4-(Dimethoxy-Phosphorylmethyl)-Benzoic Acid Methyl Ester is a key organophosphorus intermediate with a unique benzoate ester structure. This compound matters for its role in synthesizing complex molecules, particularly in the development of advanced pharmaceuticals and agrochemicals. It is primarily needed by research chemists and process development teams in the fine chemical, pharmaceutical, and crop protection industries for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of novel drug candidates, particularly those targeting the central nervous system or requiring phosphate ester functionalities.
• Agrochemical Synthesis: Serves as a precursor in the manufacture of advanced herbicides, insecticides, and plant growth regulators.
• Ligand and Catalyst Development: Used in research for creating specialized phosphonate-based ligands for metal catalysis and asymmetric synthesis.
• Material Science Research: Employed in the development of functional monomers for specialty polymers, coatings, and flame retardants.
• Chemical Biology Probes: Acts as a starting material for synthesizing probes that study enzyme activity and phosphorylation pathways.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific R&D and scale-up projects.

Basic Information

Product Name	4-(Dimethoxy-Phosphorylmethyl)-Benzoic Acid Methyl Ester
CAS No.	78022-19-2
Molecular Formula	C11H15O5P
Molecular Weight	258.21 g/mol
Synonyms	Methyl 4-[(dimethoxyphosphoryl)methyl]benzoate; Methyl p-[(dimethoxyphosphoryl)methyl]benzoate; Benzoic acid, 4-[(dimethoxyphosphoryl)methyl]-, methyl ester; Methyl 4-(dimethoxyphosphorylmethyl)benzoate; Dimethyl (4-methoxycarbonylbenzyl)phosphonate; (4-Methoxycarbonylbenzyl)phosphonic acid dimethyl ester; Phosphonic acid, P-[(4-methoxycarbonyl)phenyl]methyl]-, dimethyl ester
EINECS	Contact for details

Quality Control

Our production of 4-(Dimethoxy-Phosphorylmethyl)-Benzoic Acid Methyl Ester adheres to stringent quality protocols to ensure batch-to-batch consistency and reliability for your synthetic processes. All materials undergo comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from strong acids and incompatible organic solvents. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.