Description

Tetramethylguanidine Trifluoromethanesulfonate is a highly reactive organic salt, specifically the trifluoromethanesulfonate salt of tetramethylguanidine. This compound serves as a powerful, non-nucleophilic base and catalyst, valued for its ability to facilitate challenging organic transformations under mild conditions. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries seeking efficient synthetic pathways.

Application

• Pharmaceutical Synthesis: As a potent base and catalyst in the production of active pharmaceutical ingredients (APIs), particularly for deprotonation and condensation reactions.
• Polymer Chemistry: Catalyst for the polymerization of lactones, carbonates, and other monomers to produce high-performance polymers and plastics.
• Agrochemical Manufacturing: Used in the synthesis of advanced herbicides, fungicides, and plant growth regulators.
• Organic Synthesis Reagent: A key reagent for alkylation, acylation, and other base-mediated reactions in complex molecule construction.
• Ionic Liquid & Electrolyte Research: Component in the development of novel ionic liquids and electrolytes for battery and electrochemical applications.
• Peptide Coupling & Biochemistry: Facilitates peptide bond formation and other sensitive biochemical synthesis steps.

Basic Information

Product Name	Tetramethylguanidine Trifluoromethanesulfonate
CAS No.	77994-83-3
Molecular Formula	C7H16F3N3O3S
Molecular Weight	279.28 g/mol
Synonyms	1,1,3,3-Tetramethylguanidinium Triflate; TMG Triflate; Tetramethylguanidinium Trifluoromethanesulfonate; 1,1,3,3-Tetramethylguanidinium Trifluoromethanesulfonate; Guanidine, N,N,N',N'-tetramethyl-, trifluoromethanesulfonate (1:1); TMG TfOH; TMG·TfOH; Tetramethylguanidinium Triflate
EINECS	Contact for details

Quality Control

Our Tetramethylguanidine Trifluoromethanesulfonate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and Karl Fischer titration, to ensure high purity and consistency. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals (as Pb)	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.