Description

1,2-Cyclobutanediamine,3-Methyl-,(1-α-,2-α-,3-Bta-)-(9Ci) is a specialized chiral diamine building block of significant interest in advanced organic synthesis. Its value lies in its rigid cyclobutane backbone and stereochemically defined amine groups, which are crucial for constructing complex molecular architectures with high precision. This compound is primarily needed by research chemists and process development scientists in the pharmaceutical and agrochemical industries for applications such as asymmetric catalysis and the synthesis of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the development of novel active pharmaceutical ingredients (APIs), particularly in oncology and central nervous system (CNS) drug candidates.
• Asymmetric Ligand Precursor: Used to synthesize chiral ligands for transition metal catalysis, enabling enantioselective reactions critical for producing single-isomer compounds.
• Agrochemical Research: Serves as a building block for creating new chiral herbicides, fungicides, and plant growth regulators with improved efficacy and environmental profiles.
• Advanced Material Synthesis: Employed in the research and development of specialty polymers, dendrimers, and metal-organic frameworks (MOFs) with tailored properties.
• Academic & Process Chemistry: A valuable reagent for methodological studies in organic chemistry and for scaling up synthetic routes in process chemistry.

Basic Information

Product Name	1,2-Cyclobutanediamine,3-Methyl-,(1-α-,2-α-,3-Bta-)-(9Ci)
CAS No.	77943-27-2
Molecular Formula	C5H12N2
Molecular Weight	100.16 g/mol
Synonyms	(1R,2R,3S)-3-Methylcyclobutane-1,2-diamine; (1R,2R,3S)-3-Methyl-1,2-cyclobutanediamine; 3-Methylcyclobutane-1,2-diamine; (1α,2α,3β)-3-Methylcyclobutane-1,2-diamine; trans-3-Methylcyclobutane-1,2-diamine; Chiral Cyclobutane Diamine; 1,2-Diamino-3-methylcyclobutane
EINECS	Contact for details

Quality Control

Our 1,2-Cyclobutanediamine,3-Methyl-,(1-α-,2-α-,3-Bta-)-(9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and enantiomeric excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.