Description

Proline, 3,4-Dimethyl-, Hydrazide is a specialized derivative of the amino acid proline, featuring a hydrazide functional group. This compound is valued as a key chiral building block and intermediate in the synthesis of complex organic molecules, particularly in pharmaceutical research and development. It is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for constructing novel compounds with potential biological activity.

Application

• Pharmaceutical Intermediate: A crucial chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), especially in protease inhibitor and peptidomimetic drug discovery.
• Agrochemical Synthesis: Used in the creation of advanced, chiral pesticides and herbicides where specific stereochemistry is required for efficacy.
• Fine Chemical Building Block: Serves as a versatile starting material for custom synthesis and the production of complex specialty chemicals.
• Bioconjugation & Linker Chemistry: The reactive hydrazide group enables its use in bioconjugation strategies and as a linker molecule in chemical biology and diagnostic reagent development.
• Catalyst & Ligand Precursor: Can be utilized in the development of novel chiral catalysts and ligands for asymmetric synthesis.
• Academic & Institutional Research: Employed in university and research institute laboratories for methodological studies in organic synthesis and medicinal chemistry.

Basic Information

Product Name	Proline, 3,4-Dimethyl-, Hydrazide
CAS No.	77859-26-8
Molecular Formula	C7H14N2O2
Molecular Weight	158.20 g/mol
Synonyms	3,4-Dimethylproline hydrazide; (2S,3S,4S)-3,4-Dimethylpyrrolidine-2-carbohydrazide; L-3,4-Dimethylproline hydrazide; Hydrazide of 3,4-Dimethylproline; 2-Pyrrolidinecarboxylic acid, 3,4-dimethyl-, hydrazide; (3S,4S)-3,4-Dimethyl-L-proline hydrazide
EINECS	Contact for details

Quality Control

Our Proline, 3,4-Dimethyl-, Hydrazide is produced under a strict quality management system. Each batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the high standards required for research and synthesis. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting identity, purity, and other critical parameters.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere or in a desiccated environment after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.