Description

tert-Butyl 2-Nitroethyl Ether is a specialized organic compound featuring both an ether and a nitro functional group. This unique structure makes it a valuable intermediate for synthesizing more complex molecules in fine chemical and pharmaceutical research. It is primarily sought after by R&D chemists and process development scientists working in advanced organic synthesis. The compound's reactivity profile offers a versatile building block for constructing novel chemical entities.

Application

• Pharmaceutical Intermediate: Serves as a key synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly where the nitroethyl moiety is required for further transformation.
• Agrochemical Synthesis: Used in the production of advanced crop protection agents and herbicides, leveraging its reactivity to introduce specific functional groups.
• Organic Synthesis Building Block: Employed in academic and industrial laboratories for constructing complex organic molecules, including natural product analogs and specialty chemicals.
• Material Science Research: Acts as a precursor in the development of novel polymers or functional materials that require nitro-ether linkages.
• Cross-Coupling Reactions: Utilized in palladium-catalyzed and other metal-mediated coupling reactions to create carbon-carbon bonds.
• Nitrogen-Containing Compound Synthesis: Provides a source of the nitro group for the preparation of amines, amino acids, and other nitrogen-rich compounds through reduction or other chemical modifications.

Basic Information

Product Name	tert-Butyl 2-Nitroethyl Ether
CAS No.	77791-00-5
Molecular Formula	C6H13NO3
Molecular Weight	147.17 g/mol
Synonyms	2-Nitroethyl tert-butyl ether; 1-(tert-Butoxy)-2-nitroethane; tert-Butyl β-nitroethyl ether; 2-(tert-Butoxy)-1-nitroethane; Ether, tert-butyl 2-nitroethyl; 1-Nitro-2-tert-butoxyethane; (2-Nitroethoxy)-1,1-dimethylethane; 2-Nitro-1-tert-butoxyethane
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Nitroethyl Ether is manufactured under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including chromatographic purity analysis and identity confirmation, to ensure it meets the high standards required for research and industrial synthesis. A Certificate of Analysis (COA) detailing specific results for purity, identity, and impurities is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This material is easily oxidized and should be handled and stored under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and prevent degradation. Keep away from heat, sparks, open flames, and incompatible materials.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.