Description

2-Chloro-4-Methoxyquinazoline is a versatile and high-value heterocyclic building block in organic synthesis. This compound is critical for the development of advanced pharmaceutical intermediates and fine chemicals due to its reactive chloro and methoxy substituents. It is primarily sought after by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of kinase inhibitors and other biologically active quinazoline derivatives.
• Agrochemical Synthesis: Used in the research and development of novel herbicides and fungicides.
• Material Science Research: Serves as a building block for creating organic electronic materials and ligands for catalysis.
• Custom Synthesis & Contract Manufacturing: An essential starting material for custom synthesis projects requiring functionalized quinazoline cores.
• Academic & R&D Laboratories: Employed in medicinal chemistry programs for structure-activity relationship (SAR) studies.

Basic Information

Product Name	2-Chloro-4-Methoxyquinazoline
CAS No.	77767-98-7
Molecular Formula	C9H7ClN2O
Molecular Weight	194.62 g/mol
Synonyms	4-Methoxy-2-chloroquinazoline; 2-Chloro-4-methoxy-quinazoline; Quinazoline, 2-chloro-4-methoxy-; 2-Chloro-4-methoxy-1,3-diazanaphthalene
EINECS	Contact for details

Quality Control

Our 2-Chloro-4-Methoxyquinazoline is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and industrial synthesis. Certificates of Analysis (COA) with detailed chromatographic data are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.