Description

n-Acetylneuraminosyl Lacto-n-Noroctaosyl Ceramide is a complex, high-purity glycosphingolipid, specifically a ganglioside, that serves as a critical reference standard and research reagent in advanced biochemical studies. Its primary value lies in its role as a structurally defined molecule for investigating cell membrane dynamics, receptor interactions, and carbohydrate-mediated biological signaling pathways. This compound is essential for researchers and developers in the fields of glycobiology, immunology, and pharmaceutical development, particularly for those working on targeted therapies, vaccine adjuvants, and diagnostic tools.

Application

• Biomedical Research: Used as a high-purity standard in studies of ganglioside function, cell adhesion, and signal transduction mechanisms.
• Drug Discovery: Serves as a key intermediate or target molecule in the development of novel therapeutics for neurological disorders, cancer, and infectious diseases.
• Diagnostic Development: Employed in the design and calibration of immunoassays and biosensors that detect specific carbohydrate antigens.
• Glycoconjugate Synthesis: Acts as a sophisticated building block for the chemical or enzymatic synthesis of more complex glycostructures.
• Academic & Institutional Research: Provides a critical tool for universities and research institutes exploring the frontiers of membrane biology and glycoscience.
• Quality Control: Functions as a certified reference material (CRM) for the quality assurance of related biological products and reagents.

Basic Information

Product Name	n-Acetylneuraminosyl Lacto-n-Noroctaosyl Ceramide
CAS No.	77700-05-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Ganglioside LLG8 (Lacto-n-norhexaosylceramide IV3NeuAc); IV3NeuAc-Lc8Cer; Lacto-n-norhexaosylceramide with α-N-acetylneuraminosyl group; Sialyl-lacto-n-norhexaosylceramide; NeuAcα2-3Galβ1-3GlcNAcβ1-3Galβ1-4Glcβ1-1'Cer; Glycosphingolipid LLG8; Monosialotetrahexosylganglioside analog.
EINECS	Contact for details

Quality Control

Our n-Acetylneuraminosyl Lacto-n-Noroctaosyl Ceramide is produced under stringent conditions to ensure the highest standards of purity and structural integrity, suitable for sensitive research applications. Each batch is characterized using advanced analytical techniques including HPLC, mass spectrometry (MS), and NMR spectroscopy to confirm identity and purity. Comprehensive Certificates of Analysis (COA) detailing all critical parameters are provided to guarantee traceability and batch-to-batch consistency for your research and development needs.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). For long-term storage, it is recommended to keep the material under an inert atmosphere or desiccated conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Solvent Residue (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.