Description

O,o-Di(4-Bromophenyl)Thiophosphoryl Chloride is a high-value organophosphorus intermediate characterized by its reactive phosphoryl chloride and thiophosphoryl functional groups. This compound is essential for the synthesis of advanced chemical entities, particularly in the development of specialized ligands, flame retardants, and agrochemical active ingredients. It serves as a critical building block for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty polymer industries seeking to introduce specific bromophenyl and thiophosphoryl motifs into their target molecules.

Application

• Agrochemical Intermediate: Key precursor in the synthesis of novel insecticides, herbicides, and fungicides, leveraging the bioactive thiophosphoryl moiety.
• Pharmaceutical Synthesis: Serves as a versatile building block for creating potential pharmacologically active compounds, especially protease inhibitors or metal-chelating agents.
• Ligand and Catalyst Development: Used in organometallic chemistry to create sophisticated phosphine- or thiophosphate-based ligands for catalysis.
• Flame Retardant Synthon: Incorporated into polymer backbones or as an additive precursor to enhance flame retardancy in plastics and textiles.
• Chemical Research & Development: A valuable reagent for academic and industrial R&D exploring new reactions in organophosphorus chemistry.
• Material Science: Intermediate for modifying surface properties or creating novel monomers for specialty polymers.

Basic Information

Product Name	O,o-Di(4-Bromophenyl)Thiophosphoryl Chloride
CAS No.	77628-32-1
Molecular Formula	C12H8Br2ClOPS
Molecular Weight	450.43 g/mol
Synonyms	Bis(4-bromophenyl) Thiophosphorochloridate; Thiophosphoryl Chloride, Bis(p-bromophenyl) Ester; Phosphorochloridothioic Acid, O,O-Bis(4-bromophenyl) Ester; 4-Bromophenyl Thiophosphorodichloridate (common misnomer); p-Bromophenyl Thiophosphorochloridate; O,O-Bis(4-bromophenyl) Chlorothiophosphate
EINECS	Contact for details

Quality Control

Every batch of O,o-Di(4-Bromophenyl)Thiophosphoryl Chloride is manufactured and tested under strict quality management protocols to ensure consistency and reliability for your synthetic processes. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing key parameters such as purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring the material meets the stringent requirements for advanced intermediate use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent hydrolysis. Keep away from strong bases, oxidizing agents, and moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Melting Point	Contact for details
Related Substances (HPLC)	Total impurities ≤ 3.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.