Description

(6,8-Dichloro-4-Oxo-3-Phenyl-3,4-Dihydro-Quinazolin-2-Ylsulfanyl)-Acetic Acid is a high-purity, functionalized quinazolinone derivative designed for advanced research and synthesis. This compound serves as a critical pharmacophore and synthetic intermediate in the development of novel bioactive molecules. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers focused on creating new therapeutic agents, particularly in oncology and antimicrobial research.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel quinazolinone-based drug candidates with potential kinase inhibitory activity.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to explore and optimize biological activity profiles.
• Chemical Biology Probes: Serves as a scaffold for developing molecular probes to study specific enzyme targets and cellular pathways.
• Organic Synthesis: Utilized in heterocyclic chemistry for constructing complex molecular architectures due to its reactive thioacetic acid moiety.
• Agrochemical Research: Investigated as a precursor for developing new crop protection agents with novel modes of action.

Basic Information

Item	Details
Product Name	(6,8-Dichloro-4-Oxo-3-Phenyl-3,4-Dihydro-Quinazolin-2-Ylsulfanyl)-Acetic Acid
CAS No.	77616-01-4
Molecular Formula	C16H10Cl2N2O3S
Molecular Weight	381.23 g/mol
Synonyms	2-[(6,8-Dichloro-4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)thio]acetic acid; (6,8-Dichloro-4-oxo-3-phenyl-3,4-dihydro-2-quinazolinylthio)acetic Acid; Quinazolin-2-ylthioacetic acid derivative; 77616-01-4; 2-[(6,8-Dichloro-4-oxo-3-phenyl-3,4-dihydroquinazolin-2-yl)sulfanyl]acetic acid
EINECS	Contact for details

Quality Control

Our (6,8-Dichloro-4-Oxo-3-Phenyl-3,4-Dihydro-Quinazolin-2-Ylsulfanyl)-Acetic Acid is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.