Description

D-Glucose, 3,4,5,6-Tetrakis-o-(Trimethylsilyl)-, o-Methyloxime, 2-(1H- Indole-3-Acetate) CAS NO 77590-68-2 is a sophisticated, multi-functional chemical derivative combining a protected glucose scaffold with an indole-3-acetate moiety. This compound is specifically engineered for advanced synthetic and analytical applications, offering a versatile building block for research and development. It is primarily utilized by pharmaceutical researchers, agrochemical developers, and analytical chemists working on complex molecular synthesis, derivatization for analysis, and the development of bioactive compounds.

Application

• Pharmaceutical Intermediate: Serves as a key protected synthon in the multi-step synthesis of complex drug candidates, particularly those targeting neurological or metabolic pathways.
• Analytical Derivatization Agent: Used in Gas Chromatography (GC) and Mass Spectrometry (MS) to enhance the volatility and detectability of sensitive carbohydrate or indole-containing analytes.
• Agrochemical Research: Acts as a precursor in the development of novel plant growth regulators or herbicides, leveraging the structural features of both glucose and indole-3-acetic acid (IAA).
• Bioconjugation & Probe Development: Facilitates the creation of labeled probes for studying biological recognition events, given its reactive sites suitable for further modification.
• Glycochemistry & Glycobiology Studies: Provides a valuable tool for synthesizing protected glycoconjugates or mimicking complex carbohydrate structures in research settings.
• Chemical Biology: Employed in the design and synthesis of molecular tools to investigate enzyme mechanisms or cellular signaling pathways involving sugar and indole metabolism.

Basic Information

Product Name	D-Glucose, 3,4,5,6-Tetrakis-o-(Trimethylsilyl)-, o-Methyloxime, 2-(1H- Indole-3-Acetate)
CAS No.	77590-68-2
Molecular Formula	C33H61NO8Si4
Molecular Weight	720.22 g/mol
Synonyms	2-(1H-Indol-3-yl)acetate Derivative of 3,4,5,6-Tetra-O-trimethylsilyl-D-glucose O-Methyloxime; D-Glucose, O-methyloxime, 3,4,5,6-tetra-O-(trimethylsilyl)-, 2-(1H-indole-3-acetate); 3,4,5,6-Tetra-O-trimethylsilyl-D-glucopyranose O-Methyloxime 2-Indole-3-acetate; TMS-Glucose Methyloxime Indole Acetate; Per-TMS Glucose Methyloxime IAA Ester; 77590-68-2; (2R,3R,4S,5S,6R)-2-[(1E)-Methoxyimino]-6-[(1H-indol-3-yl)acetoxymethyl]tetrahydro-2H-pyran-3,4,5-triyl tris(trimethylsilyl) ether
EINECS	Contact for details

Quality Control

Our production of this advanced chemical intermediate adheres to strict in-process controls to ensure batch-to-batch consistency and high purity. Quality is verified through a comprehensive suite of analytical techniques including HPLC, GC, NMR, and Mass Spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles to support your R&D and quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.