Description

4-Chlorophenyl Cyclobutyl Ketone is a versatile organic building block characterized by its cyclobutyl ketone core substituted with a chlorophenyl group. This compound matters as a key synthetic intermediate in advanced organic synthesis, offering a rigid, strained cyclobutane ring system that can impart unique conformational and electronic properties to target molecules. It is primarily needed by pharmaceutical R&D laboratories and fine chemical manufacturers for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system (CNS) disorders.
• Medicinal Chemistry Research: Used as a scaffold for constructing compound libraries in drug discovery programs, enabling structure-activity relationship (SAR) studies.
• Agrochemical Synthesis: Acts as a building block for developing new generation herbicides and pesticides with enhanced efficacy.
• Ligand and Catalyst Development: Employed in the preparation of specialized ligands for asymmetric catalysis and organometallic complexes.
• Material Science Research: Utilized in the synthesis of organic semiconductors, liquid crystals, or polymers with tailored photophysical properties.
• Academic & Industrial R&D: A valuable reagent for methodological development in organic synthesis, including ring-opening and cross-coupling reactions.

Basic Information

Product Name	4-Chlorophenyl Cyclobutyl Ketone
CAS No.	77585-25-2
Molecular Formula	C11H11ClO
Molecular Weight	194.66 g/mol
Synonyms	1-(4-Chlorophenyl)cyclobutan-1-one; 4-Chloro-α-cyclobutylbenzyl ketone; Cyclobutyl 4-chlorophenyl ketone; p-Chlorophenyl cyclobutyl ketone; 4'-Chlorocyclobutyrophenone; (4-Chlorophenyl)(cyclobutyl)methanone; CAS 77585-25-2
EINECS	Contact for details

Quality Control

Our 4-Chlorophenyl Cyclobutyl Ketone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements of research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and quality assurance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.