Description

6-Chloro-3-(4-Chlorophenyl)-2,4-Bis(2-Fluorophenyl)-3,4-Dihydroquinazolin-4-Ol is a high-purity, complex heterocyclic compound of significant interest in advanced organic synthesis. This specialty chemical serves as a critical pharmaceutical intermediate for the development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring sophisticated molecular scaffolds. It is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors seeking to build complex quinazolinone-based structures.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Research: Used in the development of new-generation herbicides and pesticides with specific activity profiles.
• Chemical Biology Probe: Serves as a core structure for creating molecular probes to study enzyme inhibition and protein-ligand interactions.
• Material Science Precursor: Potential intermediate in the synthesis of organic electronic materials and specialty polymers.
• Academic & Industrial R&D: Fundamental reagent for methodological studies in organic chemistry and heterocyclic compound synthesis.

Basic Information

Product Name	6-Chloro-3-(4-Chlorophenyl)-2,4-Bis(2-Fluorophenyl)-3,4-Dihydroquinazolin-4-Ol
CAS No.	77549-03-2
Molecular Formula	C26H16Cl2F2N2O
Molecular Weight	469.32 g/mol
Synonyms	6-Chloro-3-(4-chlorophenyl)-2,4-bis(2-fluorophenyl)-3,4-dihydro-4-quinazolinol; 3,4-Dihydro-6-chloro-3-(4-chlorophenyl)-2,4-bis(2-fluorophenyl)-4-quinazolinol; 4-Quinazolinol, 6-chloro-3-(4-chlorophenyl)-2,4-bis(2-fluorophenyl)-3,4-dihydro-; CAS 77549-03-2; 6-Chloro-3-(4-chlorophenyl)-2,4-di(2-fluorophenyl)-3,4-dihydroquinazolin-4-ol
EINECS	Contact for details

Quality Control

Our 6-Chloro-3-(4-Chlorophenyl)-2,4-Bis(2-Fluorophenyl)-3,4-Dihydroquinazolin-4-Ol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding R&D and scale-up projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound may be light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed when not in use to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.