Description

(R)-2-[(1R,8Ar)-Octahydro-4Aβ-Methylspiro[Naphthalene-1(8Ah),2'-Oxirane]-7β-Yl]-1,2-Propanediol is a high-purity, stereochemically defined organic compound featuring a complex spirocyclic and oxirane (epoxide) structure. This compound is of significant value as a sophisticated chiral building block or intermediate in advanced organic synthesis. It is primarily needed by research and development teams in the pharmaceutical, agrochemical, and specialty chemical industries for the synthesis of novel active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, particularly in areas requiring complex stereochemistry.
• Agrochemical Synthesis: Used in the development of advanced, enantiomerically pure pesticides or herbicides where specific stereochemistry impacts biological activity.
• Asymmetric Catalysis Ligand Precursor: Serves as a starting material for synthesizing chiral ligands used in asymmetric catalytic reactions.
• Fine Chemical Production: Employed in the multistep synthesis of high-value specialty chemicals and flavors/fragrances.
• Academic & Industrial Research: A valuable compound for methodological studies in organic chemistry, particularly in stereoselective synthesis and ring-opening reactions of epoxides.

Basic Information

Product Name	(R)-2-[(1R,8Ar)-Octahydro-4Aβ-Methylspiro[Naphthalene-1(8Ah),2'-Oxirane]-7β-Yl]-1,2-Propanediol
CAS No.	77521-41-6
Molecular Formula	C₁₅H₂₄O₃
Molecular Weight	252.35 g/mol
Synonyms	(7R,8aS)-7-[(1R)-1,2-Dihydroxypropyl]octahydro-4a-methylspiro[naphthalene-1,2'-oxirane]; (R)-2-[(1R,8aS)-Octahydro-4a-methylspiro[naphthalene-1(8aH),2'-oxiran]-7-yl]-1,2-propanediol; Spiro[oxirane-2,1'(8aH)-naphthalene] derivative; CAS 77521-41-6; Chiral spirocyclic diol epoxide; (1R,4aS,7R,8aR)-7-(1,2-Dihydroxypropyl)-1-methyl-1,2,3,4,4a,5,6,8a-octahydronaphthalen-1-yloxirane
EINECS	Contact for details

Quality Control

Our (R)-2-[(1R,8Ar)-Octahydro-4Aβ-Methylspiro[Naphthalene-1(8Ah),2'-Oxirane]-7β-Yl]-1,2-Propanediol is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric purity and standard spectroscopic methods for identity confirmation, to ensure it meets the high standards required for research and synthesis. Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from strong oxidizing agents. For long-term storage under an inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.