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(R)-(+)-1,2-Epoxyoctane CAS NO 77495-66-0


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CAS No.:77495-66-0

Grade:Pharmacy Grade

Content:99.9%

Brand:Customizable

Packaging:Customizable

Description

(R)-(+)-1,2-Epoxyoctane CAS NO 77495-66-0 is a high-purity, chiral epoxide building block essential for asymmetric synthesis. Its value lies in its ability to introduce the (R)-configured oxirane moiety into target molecules with high stereochemical fidelity, enabling the production of enantiomerically pure intermediates. This compound is critically needed by researchers and process chemists in the pharmaceutical, agrochemical, and advanced materials industries for developing novel active ingredients and functional polymers.

Application

  • Pharmaceutical Intermediate: Key chiral synthon for the synthesis of enantiomerically pure drugs, particularly in constructing β-blockers, antifungal agents, and other bioactive molecules.
  • Agrochemical Synthesis: Used in the production of chiral pesticides and herbicides where specific stereochemistry is required for optimal activity and environmental profile.
  • Polymer & Material Science: Serves as a monomer or cross-linking agent for creating specialty polymers with tailored properties, such as epoxy resins or chiral stationary phases for chromatography.
  • Asymmetric Catalysis Research: A valuable substrate for developing and testing new chiral catalysts and methodologies in academic and industrial R&D settings.
  • Fine Chemical Production: Employed in the multi-step synthesis of complex flavors, fragrances, and other high-value specialty chemicals.

Basic Information

Product Name (R)-(+)-1,2-Epoxyoctane
CAS No. 77495-66-0
Molecular Formula C8H16O
Molecular Weight 128.21 g/mol
Synonyms (R)-(+)-Octylene Oxide; (R)-1,2-Epoxyoctane; (R)-Octane-1,2-epoxide; (+)-(R)-1,2-Epoxyoctane; (2R)-2-Octyloxirane; (R)-Octyloxirane; (R)-1,2-Octylene Oxide; (R)-Octene Oxide
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Quality Control

Our (R)-(+)-1,2-Epoxyoctane is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity assessment by GC or HPLC, to ensure it meets the high standards required for synthetic applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profile is provided with every shipment to guarantee traceability and consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from heat, sparks, open flames, and strong oxidizing agents. Due to its light-sensitive nature, containers should be amber glass or otherwise opaque.

Specification

Item Specification
Appearance Clear, colorless to pale yellow liquid
Identification (IR) Conforms to structure
Purity (GC) ≥ 98.0%
Enantiomeric Excess (Chiral GC/HPLC) ≥ 99.0%
Water Content (KF) ≤ 0.5%
Refractive Index (n20D) 1.420 - 1.424
Specific Rotation ([α]20D) +10.0° to +12.0° (c=1, CHCl3)

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.

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