Description

6-Nitro-2-Piperazin-1-Yl-Quinoline is a high-purity, nitrogen-containing heterocyclic compound that serves as a critical synthetic intermediate. Its value lies in its versatile piperazinyl-quinoline scaffold, which is a privileged structure in medicinal chemistry for developing bioactive molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for the synthesis of novel therapeutic agents and advanced chemical entities.

Application

• Pharmaceutical Intermediate: A key building block for the research and development of potential drug candidates, especially those targeting central nervous system (CNS) disorders, infectious diseases, and oncology.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and combinatorial chemistry to create libraries of novel quinoline derivatives with optimized biological activity.
• Agrochemical Synthesis: Serves as a precursor in the development of new pesticides, herbicides, or fungicides that leverage the quinoline core for enhanced efficacy.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.
• Organic Synthesis: Acts as a versatile intermediate for further functionalization, enabling the creation of complex molecules for material science or specialty chemical applications.

Basic Information

Product Name	6-Nitro-2-Piperazin-1-Yl-Quinoline
CAS No.	77372-73-7
Molecular Formula	C₁₃H₁₅N₅O₂
Molecular Weight	273.29 g/mol
Synonyms	2-(1-Piperazinyl)-6-nitroquinoline; 6-Nitro-2-(piperazin-1-yl)quinoline; 6-Nitro-2-piperazinylquinoline; Quinoline, 6-nitro-2-(1-piperazinyl)-; 6-Nitro-2-(1-piperazinyl)quinoline; 77372-73-7; 6-Nitro-2-piperazin-1-ylquinoline
EINECS	Contact for details

Quality Control

Our 6-Nitro-2-Piperazin-1-Yl-Quinoline is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to confirm identity and purity. A Certificate of Analysis (COA) detailing all test results is provided with every shipment, ensuring full traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider conditions under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.