Description

Lithium Diisobutyl-tert-Butoxyaluminum Hydride is a highly selective and versatile reducing agent, specifically a sterically hindered aluminum hydride complex. Its primary value lies in its ability to perform chemoselective reductions of carbonyl compounds, such as aldehydes and ketones, with excellent functional group tolerance, often under mild conditions. This makes it an essential reagent for synthetic organic chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Selective Carbonyl Reduction: Preferred for the controlled reduction of aldehydes and ketones in the presence of other sensitive functional groups like esters, nitriles, and epoxides.
• Pharmaceutical Intermediate Synthesis: Key reagent in multi-step synthesis for producing chiral alcohols and other high-value intermediates in active pharmaceutical ingredient (API) development.
• Fine Chemical Manufacturing: Used in the production of specialty chemicals, flavors, fragrances, and liquid crystal materials where precise reduction is critical.
• Polymer Chemistry: Acts as a catalyst or co-catalyst component in Ziegler-Natta type polymerization and other organometallic-mediated reactions.
• Academic & R&D Laboratories: A staple reagent for methodological development and exploratory synthesis in organic and organometallic chemistry research.
• Asymmetric Synthesis: Employed in conjunction with chiral ligands or precursors for the synthesis of enantiomerically enriched compounds.

Basic Information

Item	Details
Product Name	Lithium Diisobutyl-tert-Butoxyaluminum Hydride
CAS No.	77299-63-9
Molecular Formula	C12H28AlLiO
Molecular Weight	222.28 g/mol
Synonyms	Lithium Diisobutyl-tert-butoxyaluminum Hydride; LDBBA; Lithium Diisobutyl(tert-butoxy)aluminum Hydride; Diisobutyl(tert-butoxy)aluminum Lithium Hydride; (tert-Butoxy)diisobutylaluminum Lithium Hydride; Lithium (tert-Butoxy)diisobutylaluminum Hydride; LDBBA-H; Sterically Hindered Aluminum Hydride Reducing Agent
EINECS	Contact for details

Quality Control

Our Lithium Diisobutyl-tert-Butoxyaluminum Hydride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high reactivity. Each lot is analyzed to confirm identity, purity, and solution concentration. We provide comprehensive Certificates of Analysis (COA) detailing all relevant specifications. Our quality system is designed to meet the stringent requirements of GMP and ISO standards for advanced chemical synthesis.

Storage

Preserve in a tightly closed container, protected from light. This material is strictly light-sensitive (protect from all light exposure), hygroscopic (moisture-sensitive), and easily oxidized (store under inert atmosphere). For long-term stability, store under a dry, inert atmosphere (argon or nitrogen) at 2-8°C. Keep away from heat, sparks, and open flames. Use only in a well-ventilated area or fume hood.

Specification

Item	Specification
Appearance	Colorless to pale yellow solution
Identification (IR)	Conforms
Assay (as Al complex)	≥ 95.0%
Concentration (in solvent)	Typically 1.0 M in THF or Hexanes
Active Hydride Content	Contact for details
Moisture (Karl Fischer)	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.