Description

Glycine tert-Butyl Ester Dibenzenesulfimide Salt is a protected amino acid derivative widely used as a key synthetic intermediate in organic and medicinal chemistry. Its primary value lies in providing a versatile glycine building block with orthogonal protecting groups, enabling selective peptide bond formation and complex molecule assembly. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries, particularly for developing active pharmaceutical ingredients (APIs) and novel bioactive compounds.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of peptides, peptidomimetics, and complex drug molecules.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and plant growth regulators.
• Peptide Chemistry: Serves as a protected glycine unit in solid-phase and solution-phase peptide synthesis (SPPS).
• Chemical Biology Research: Employed in the development of probes, inhibitors, and tool compounds for studying biological processes.
• Custom Synthesis: A valuable starting material for contract research organizations (CROs) and CDMOs producing bespoke organic molecules.
• Material Science: Potential precursor for specialty polymers and functionalized materials requiring amino acid motifs.

Basic Information

Product Name	Glycine tert-Butyl Ester Dibenzenesulfimide Salt
CAS No.	77284-30-1
Molecular Formula	C19H24N2O4S2
Molecular Weight	408.53 g/mol
Synonyms	Glycine, N-(benzenesulfonyl)-, 1,1-dimethylethyl ester, benzenesulfonamide salt; N-(Benzenesulfonyl)glycine tert-Butyl Ester Benzenesulfonamide Salt; tert-Butyl N-(phenylsulfonyl)glycinate Benzenesulfonamide Salt; Bs-Gly-OtBu·BsNH2; N-Bs-Glycine OtBu ester sulfimide salt; Glycine, N-(phenylsulfonyl)-, 1,1-dimethylethyl ester, compd. with benzenesulfonamide (1:1)
EINECS	Contact for details

Quality Control

Our Glycine tert-Butyl Ester Dibenzenesulfimide Salt is produced under strict quality management protocols. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting compliance in GMP-aligned synthesis workflows.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.