Description

(2-Hydroxy-2-Phenyl-Ethyl)-Methyl-Carbamic Acid tert-Butyl Ester CAS NO 77184-09-9 is a specialized carbamate derivative, serving as a crucial protected intermediate in advanced organic synthesis. Its primary value lies in providing a versatile building block for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and fine chemical manufacturers engaged in the synthesis of active pharmaceutical ingredients (APIs) and other high-value nitrogen-containing compounds.

Application

• Pharmaceutical Intermediate: Key building block in the multi-step synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in the exploration and development of new therapeutic agents, leveraging its protected amine and alcohol functionalities.
• Peptidomimetic Synthesis: Serves as a precursor for constructing non-peptide scaffolds that mimic the biological activity of peptides.
• Chiral Synthesis: Utilized in asymmetric synthesis routes due to the presence of a chiral center, enabling the production of enantiomerically pure compounds.
• Agrochemical Development: Potential intermediate in the research and synthesis of advanced crop protection agents and pesticides.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for bespoke chemical production projects.

Basic Information

Product Name	(2-Hydroxy-2-Phenyl-Ethyl)-Methyl-Carbamic Acid tert-Butyl Ester
CAS No.	77184-09-9
Molecular Formula	C14H21NO3
Molecular Weight	251.32 g/mol
Synonyms	tert-Butyl N-[(2S)-2-hydroxy-2-phenylethyl]-N-methylcarbamate; N-[(2S)-2-Hydroxy-2-phenylethyl]-N-methylcarbamic Acid 1,1-Dimethylethyl Ester; (S)-tert-Butyl (2-hydroxy-2-phenylethyl)(methyl)carbamate; (S)-N-Boc-N-methyl-2-phenyl-2-aminoethanol; Boc-N-Me-PEA; (S)-2-((tert-Butoxycarbonyl)(methyl)amino)-1-phenylethanol; (S)-N-Methyl-N-Boc-2-amino-2-phenylethanol
EINECS	Contact for details

Quality Control

Our (2-Hydroxy-2-Phenyl-Ethyl)-Methyl-Carbamic Acid tert-Butyl Ester is produced under strict quality management systems. We offer material suitable for research and development use, with typical purity grades exceeding 95% (HPLC). Each batch is supported by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. Specifications can be tailored to meet the stringent requirements of cGMP (current Good Manufacturing Practice) for advanced pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, containers should be kept tightly sealed and under an inert atmosphere for long-term storage to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.