Description

(R-(E))-2-(1-Naphthalenyl)-1-(3-Phenyl-2-Propenyl)Piperidine is a chiral, nitrogen-containing organic compound featuring a piperidine core substituted with naphthalene and cinnamyl groups. This specific stereochemistry makes it a valuable advanced pharmaceutical intermediate (API) and a versatile building block in asymmetric synthesis. It is primarily utilized by research institutions and manufacturers in the pharmaceutical and fine chemical industries for the development of new active ingredients and complex molecules.

Application

• Pharmaceutical Intermediate: Serves as a key chiral precursor in the synthesis of potential drug candidates, particularly those targeting neurological or receptor-based pathways.
• Asymmetric Synthesis: Acts as a sophisticated ligand or building block in catalytic and stoichiometric asymmetric reactions to induce chirality in target molecules.
• Medicinal Chemistry Research: Used in high-throughput screening and structure-activity relationship (SAR) studies to explore new bioactive compounds.
• Fine Chemical Production: Employed in the multi-step synthesis of complex, high-value specialty chemicals for agrochemicals or material science.
• Reference Standard: Supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	(R-(E))-2-(1-Naphthalenyl)-1-(3-Phenyl-2-Propenyl)Piperidine
CAS No.	77184-03-3
Molecular Formula	C24H25N
Molecular Weight	327.47 g/mol
Synonyms	(R,E)-2-(Naphthalen-1-yl)-1-(3-phenylallyl)piperidine; (R)-(E)-1-Cinnamyl-2-(1-naphthyl)piperidine; (R,E)-1-Cinnamyl-2-(1-naphthyl)piperidine; (R,E)-N-Cinnamyl-2-(1-naphthyl)piperidine; (R,E)-2-(1-Naphthyl)-1-(3-phenyl-2-propen-1-yl)piperidine; (R,E)-1-(3-Phenyl-2-propenyl)-2-(1-naphthalenyl)piperidine; (R,E)-2-(1-Naphthyl)-1-(cinnamyl)piperidine
EINECS	Contact for details

Quality Control

Our (R-(E))-2-(1-Naphthalenyl)-1-(3-Phenyl-2-Propenyl)Piperidine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure it meets the high standards required for pharmaceutical R&D and synthesis. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) to minimize oxidation and degradation. Keep the container in a cool, dry, and well-ventilated place away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.