Description

(2R)-2-Naphthylpiperidine CAS NO 77184-01-1 is a chiral piperidine derivative featuring a naphthyl substituent, serving as a valuable chiral building block and intermediate in advanced organic synthesis. Its enantiomerically pure structure is critical for imparting specific stereochemical properties in the development of active pharmaceutical ingredients and functional materials. This compound is primarily needed by research institutions and industrial manufacturers in the pharmaceutical, agrochemical, and specialty chemical sectors for applications in asymmetric synthesis and medicinal chemistry.

Application

• Chiral intermediate in the synthesis of pharmaceutical candidates, particularly for central nervous system (CNS) active compounds.
• Building block for the development of enantioselective catalysts and ligands used in asymmetric synthesis.
• Key starting material in agrochemical research for creating novel, stereochemically defined active ingredients.
• Precursor in the synthesis of advanced materials, such as liquid crystals or organic semiconductors, where the naphthyl group contributes to π-conjugation.
• Reference standard and reagent in analytical and medicinal chemistry research for method development and biological screening.
• Intermediate for the preparation of complex natural product analogs and other fine chemicals requiring a chiral piperidine scaffold.

Basic Information

Product Name	(2R)-2-Naphthylpiperidine
CAS No.	77184-01-1
Molecular Formula	C₁₅H₁₇N
Molecular Weight	211.30 g/mol
Synonyms	(R)-2-(Naphthalen-2-yl)piperidine; (R)-2-(2-Naphthyl)piperidine; (2R)-2-(2-Naphthyl)piperidine; (R)-2-Naphth-2-yl-piperidine; 2-Naphthylpiperidine, (2R)-; (+)-(R)-2-(2-Naphthyl)piperidine; (R)-2-Naphthylpiperidine; Piperidine, 2-(2-naphthyl)-, (2R)-
EINECS	Contact for details

Quality Control

Our (2R)-2-Naphthylpiperidine is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity analysis, to ensure it meets the high standards required for research and industrial use. Certificates of Analysis (COA) with detailed chromatographic data (HPLC, GC) and specific rotation values are provided to guarantee identity, purity, and enantiomeric excess.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Enantiomeric Excess)	≥ 98.0% ee
Melting Point	Contact for details
Specific Rotation	Contact for details
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.