Description

Ethyl 4-Chloro-7-Methoxyquinoline-3-Carboxylate is a high-purity, versatile quinoline derivative serving as a critical building block in advanced organic synthesis. This compound is essential for researchers and manufacturers requiring a reliable, high-quality intermediate to develop novel active pharmaceutical ingredients (APIs) and functional materials. It is primarily utilized by the pharmaceutical, agrochemical, and specialty chemical industries for the research and production of complex molecules.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of various quinoline-based drug candidates, including potential antimicrobial and anticancer agents.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the bioactive quinoline scaffold.
• Organic Synthesis Building Block: Employed in complex multi-step syntheses to construct more elaborate heterocyclic systems and functional molecules.
• Material Science Research: Investigated as a monomer or precursor for the creation of specialty polymers and organic electronic materials.
• Chemical Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	Ethyl 4-Chloro-7-Methoxyquinoline-3-Carboxylate
CAS No.	77156-85-5
Molecular Formula	C₁₃H₁₂ClNO₃
Molecular Weight	265.69 g/mol
Synonyms	4-Chloro-7-methoxyquinoline-3-carboxylic acid ethyl ester; Ethyl 4-chloro-7-methoxy-3-quinolinecarboxylate; 3-Quinolinecarboxylic acid, 4-chloro-7-methoxy-, ethyl ester; 7-Methoxy-4-chloroquinoline-3-carboxylic acid ethyl ester; 4-Chloro-7-methoxyquinoline-3-carboxylic acid ethyl ester; Ethyl 4-chloro-7-methoxyquinoline-3-carboxylate; 77156-85-5
EINECS	Contact for details

Quality Control

Our Ethyl 4-Chloro-7-Methoxyquinoline-3-Carboxylate is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing specifications such as identity, purity (by HPLC), and impurity profiles. We support compliance with cGMP and ICH guidelines for pharmaceutical intermediates, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.