Description

Ethyl 4-Chloro-5,8-Dimethoxyquinoline-3-Carboxylate is a high-purity, synthetically valuable quinoline derivative. This compound serves as a critical advanced pharmaceutical intermediate and a versatile building block in organic synthesis. It is primarily required by R&D chemists and process development teams in the pharmaceutical, agrochemical, and fine chemical industries for the development of novel active compounds.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of complex drug candidates, particularly those with quinoline-based pharmacophores.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its heterocyclic structure for bioactivity.
• Organic Synthesis Building Block: Employed in medicinal chemistry for constructing more complex molecules via reactions at the ester, chloro, or methoxy functional groups.
• Material Science Research: Investigated as a potential monomer or additive for creating specialty polymers with unique optical or electronic properties.
• Academic & Institutional R&D: Serves as a standard or starting material in university and contract research organization laboratories for methodological studies.

Basic Information

Product Name	Ethyl 4-Chloro-5,8-Dimethoxyquinoline-3-Carboxylate
CAS No.	77156-82-2
Molecular Formula	C₁₄H₁₄ClNO₄
Molecular Weight	295.72 g/mol
Synonyms	4-Chloro-5,8-dimethoxyquinoline-3-carboxylic acid ethyl ester; Ethyl 4-chloro-5,8-dimethoxy-3-quinolinecarboxylate; 3-Quinolinecarboxylic acid, 4-chloro-5,8-dimethoxy-, ethyl ester; 77156-82-2; 5,8-Dimethoxy-4-chloroquinoline-3-carboxylic acid ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 4-Chloro-5,8-Dimethoxyquinoline-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and structural identity. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with every shipment to guarantee batch-to-batch consistency for your critical R&D and scale-up processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.