Description

8-Cyano-4-Hydroxyquinoline-3-Carboxylic Acid Ethyl Ester is a high-value, multi-functional quinoline derivative used as a critical synthetic intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in the development of advanced pharmaceutical agents and specialty organic materials. It is primarily needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for synthesizing novel active compounds.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting infectious diseases or with kinase inhibitory activity.
• Agrochemical Research: Used in the development of new herbicides, fungicides, or plant growth regulators due to its bioactive quinoline core.
• Organic Synthesis Reagent: Serves as a versatile precursor for constructing complex heterocyclic compounds in academic and industrial research laboratories.
• Material Science: Potential use in the development of organic semiconductors, ligands for metal-organic frameworks (MOFs), or fluorescent markers.
• Chemical Biology Probe: Can be utilized to create molecular probes for studying biological pathways and enzyme functions.

Basic Information

Product Name	8-Cyano-4-Hydroxyquinoline-3-Carboxylic Acid Ethyl Ester
CAS No.	77156-79-7
Molecular Formula	C₁₃H₁₀N₂O₃
Molecular Weight	242.23 g/mol
Synonyms	Ethyl 8-Cyano-4-hydroxyquinoline-3-carboxylate; 4-Hydroxy-8-cyanoquinoline-3-carboxylic Acid Ethyl Ester; 3-Quinolinecarboxylic acid, 8-cyano-4-hydroxy-, ethyl ester; 8-Cyano-4-hydroxy-3-quinolinecarboxylic acid ethyl ester; Ethyl 4-hydroxy-8-cyanoquinoline-3-carboxylate; 77156-79-7; Quinoline-3-carboxylic acid, 8-cyano-4-hydroxy-, ethyl ester
EINECS	Contact for details

Quality Control

Our 8-Cyano-4-Hydroxyquinoline-3-Carboxylic Acid Ethyl Ester is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via FT-IR and NMR spectroscopy, to ensure it meets the high standards required for research and development applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.