Description

Ethyl 4-Hydroxy-6-Methoxyquinoline-3-Carboxylate is a high-purity quinoline derivative serving as a critical advanced intermediate in organic synthesis. Its value lies in providing a versatile, functionalized scaffold for constructing complex molecules with potential biological activity. This compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel quinoline-based drug candidates, particularly for antimicrobial, anticancer, and anti-inflammatory applications.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging the bioactive quinoline core.
• Material Science: Serves as a precursor for functional organic materials, including ligands for metal-organic frameworks (MOFs) and organic semiconductors.
• Academic & R&D: Essential reagent in medicinal chemistry and organic synthesis research for exploring new chemical entities and reaction pathways.
• Dye & Pigment Intermediate: Potential starting material for synthesizing specialized quinoline dyes and fluorescent markers.

Basic Information

Product Name	Ethyl 4-Hydroxy-6-Methoxyquinoline-3-Carboxylate
CAS No.	77156-78-6
Molecular Formula	C₁₃H₁₃NO₄
Molecular Weight	247.25 g/mol
Synonyms	4-Hydroxy-6-methoxyquinoline-3-carboxylic acid ethyl ester; Ethyl 4-hydroxy-6-methoxy-3-quinolinecarboxylate; 3-Quinolinecarboxylic acid, 4-hydroxy-6-methoxy-, ethyl ester; 6-Methoxy-4-hydroxyquinoline-3-carboxylic acid ethyl ester; A-77636; 4-Hydroxy-6-methoxyquinoline-3-carboxylate ethyl ester
EINECS	Contact for details

Quality Control

Our Ethyl 4-Hydroxy-6-Methoxyquinoline-3-Carboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (IR, NMR), to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.