Description

1-Amino-3-([(Benzyloxy)Carbonyl]Amino)Propan-1-Iminium Chloride is a protected amino acid derivative, specifically a Cbz-protected diaminopropane iminium salt, serving as a versatile and high-purity synthetic building block. Its primary value lies in enabling controlled amide bond formation and peptide chain elongation in complex organic syntheses, particularly for research and pharmaceutical development. This compound is essential for medicinal chemists and process development scientists working on novel active pharmaceutical ingredients (APIs), peptide mimetics, and specialized fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of complex drug candidates, especially those containing diamine or polyamine structures.
• Peptide Synthesis: Used as a protected amino acid derivative in solid-phase and solution-phase peptide synthesis to introduce specific functional groups.
• Bioconjugation & Linker Chemistry: Employed in the development of antibody-drug conjugates (ADCs) and other bioconjugates where a controlled, reactive amine is required.
• Chemical Biology Research: Serves as a tool compound for studying enzyme inhibition, receptor binding, and other biochemical pathways.
• Fine Chemical Manufacturing: Integral to the production of specialty chemicals, catalysts, and ligands used in asymmetric synthesis.
• Agrochemical Development: Potential intermediate in the synthesis of novel herbicides, fungicides, or plant growth regulators.

Basic Information

Product Name	1-Amino-3-([(Benzyloxy)Carbonyl]Amino)Propan-1-Iminium Chloride
CAS No.	77153-01-6
Molecular Formula	C11H16ClN3O2
Molecular Weight	257.72 g/mol
Synonyms	N-Carbobenzoxy-1,3-diaminopropane Hydrochloride; Cbz-DAP·HCl; (3-Aminopropyl)carbamic acid benzyl ester hydrochloride; 1,3-Diaminopropane, N1-(benzyloxycarbonyl)-, monohydrochloride; Z-1,3-Diaminopropane hydrochloride; Nα-Cbz-1,3-diaminopropane HCl; Benzyl N-(3-aminopropyl)carbamate hydrochloride
EINECS	Contact for details

Quality Control

Our 1-Amino-3-([(Benzyloxy)Carbonyl]Amino)Propan-1-Iminium Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for research and pharmaceutical applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.