Description

8-Bromo-4(1H)-Quinazolinone is a versatile brominated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for constructing complex molecular architectures, particularly in the development of novel pharmaceuticals and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of quinazolinone-based drug candidates, including kinase inhibitors and anticancer agents.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging the bioactive quinazolinone scaffold.
• Material Science: Acts as a building block for creating organic electronic materials and advanced polymers with specific optical or electronic properties.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological studies and the exploration of new heterocyclic chemistry.
• Chemical Library Synthesis: A valuable reagent for generating diverse compound libraries for high-throughput screening in drug discovery programs.

Basic Information

Product Name	8-Bromo-4(1H)-Quinazolinone
CAS No.	77150-35-7
Molecular Formula	C8H5BrN2O
Molecular Weight	225.04 g/mol
Synonyms	8-Bromo-4-hydroxyquinazoline; 8-Bromoquinazolin-4(1H)-one; 4(1H)-Quinazolinone, 8-bromo-; 77150-35-7; 8-Bromo-1,4-dihydroquinazolin-4-one; 8-Bromo-4-quinazolinol; 8-Bromoquinazolin-4-ol
EINECS	Contact for details

Quality Control

Our 8-Bromo-4(1H)-Quinazolinone is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure consistency and compliance with customer specifications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. For long-term storage, consider under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.