Description

4(1H)-Quinazolinone, 2-(1-Chloro-1-Methylethyl)-8-Methoxy- (9Ci) is a specialized heterocyclic organic compound belonging to the quinazolinone class, a scaffold of significant interest in medicinal chemistry. Its core value lies in serving as a crucial pharmaceutical intermediate and a versatile building block for the synthesis of more complex molecules. This high-purity compound is primarily needed by research institutions and pharmaceutical companies engaged in the development of new active pharmaceutical ingredients (APIs), particularly for applications in oncology and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel drug candidates, especially kinase inhibitors and other targeted therapies.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and the design of new chemical entities with potential biological activity.
• Organic Synthesis Building Block: Used in multi-step synthetic routes to construct complex heterocyclic systems due to its reactive functional groups.
• Biochemical Research: Employed in the study of enzyme inhibition and other biochemical pathways as a tool compound.
• Agrochemical Research: Potential intermediate in the development of new pesticides or herbicides, leveraging its heterocyclic structure.
• Academic & Industrial R&D: Fundamental material for exploratory chemistry and process development in both university and corporate laboratory settings.

Basic Information

Product Name	4(1H)-Quinazolinone, 2-(1-Chloro-1-Methylethyl)-8-Methoxy- (9Ci)
CAS No.	76983-58-9
Molecular Formula	C₁₃H₁₅ClN₂O₂
Molecular Weight	266.72 g/mol
Synonyms	2-(1-Chloro-1-methylethyl)-8-methoxy-4(1H)-quinazolinone; 2-(2-Chloropropan-2-yl)-8-methoxy-1,4-dihydroquinazolin-4-one; 8-Methoxy-2-(1-chloro-1-methylethyl)-4(1H)-quinazolinone; 2-(α-Chloroisopropyl)-8-methoxy-4(1H)-quinazolinone; Quinazolinone derivative (CAS 76983-58-9); 8-Methoxy-2-(2-chloro-2-propyl)-4-quinazolinone
EINECS	Contact for details

Quality Control

Our 4(1H)-Quinazolinone, 2-(1-Chloro-1-Methylethyl)-8-Methoxy- (9Ci) is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and MS, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials such as strong oxidizing agents. For long-term storage, consider storing under an inert atmosphere to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.