Description

(1R,4R)-Bicyclo[2.2.2]Octane-2,5-Dione is a high-purity, stereochemically defined bicyclic diketone. This compound is a valuable chiral building block and synthetic intermediate, prized for its rigid, three-dimensional structure which is instrumental in constructing complex molecular architectures. It is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require precise stereochemistry and high chemical purity for their synthetic processes.

Application

• Pharmaceutical Intermediate: A key chiral precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for drugs targeting the central nervous system.
• Ligand and Catalyst Synthesis: Used to construct sophisticated chiral ligands and organocatalysts for asymmetric synthesis.
• Agrochemical Research: Serves as a core scaffold in the development of novel herbicides and pesticides with specific stereochemical requirements.
• Material Science: Acts as a monomer or cross-linking agent for the production of specialty polymers with unique thermal and mechanical properties.
• Academic & R&D: A fundamental reagent in organic chemistry research for methodology development and total synthesis of natural products.
• Flavor & Fragrance Chemistry: Potential intermediate for synthesizing musky or woody odorants with high stability.

Basic Information

Product Name	(1R,4R)-Bicyclo[2.2.2]Octane-2,5-Dione
CAS No.	76478-53-0
Molecular Formula	C8H10O2
Molecular Weight	138.16 g/mol
Synonyms	(1R,4R)-Bicyclo[2.2.2]octane-2,5-dione; (1R,4R)-2,5-Diketobicyclo[2.2.2]octane; (1R,4R)-2,5-Dioxobicyclo[2.2.2]octane; (1R,4R)-Bicyclo[2.2.2]octane-2,5-dione; (1R,4R)-BCO-2,5-dione; (1R,4R)-BCO-dione; (1R,4R)-2,5-Bicyclo[2.2.2]octanedione; (1R,4R)-2,5-Diketo-bicyclo[2.2.2]octane
EINECS	Contact for details

Quality Control

Our (1R,4R)-Bicyclo[2.2.2]Octane-2,5-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chiral purity and chemical identity. Certificates of Analysis (COA) detailing specifications for assay, enantiomeric excess, and impurity profiles are available upon request to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.