Description

3H-Diazirine-3,3-Dicarboxylic Acid Dipotassium Salt is a versatile and highly reactive diazirine-based photoaffinity labeling reagent. This compound is valued for its ability to form covalent bonds upon photolysis with UV light, making it an essential tool for probing biomolecular interactions and mapping binding sites. It is primarily sought by researchers and manufacturers in the fields of chemical biology, pharmaceutical development, and proteomics for applications in photo-crosslinking and target identification studies.

Application

• Photoaffinity Labeling (PAL): A key reagent for covalently tagging proteins, nucleic acids, and other biomolecules upon UV irradiation to study interaction sites.
• Proteomics and Chemical Biology: Used in activity-based protein profiling (ABPP) and the development of probes for target identification and validation in drug discovery.
• Bioconjugation and Linker Chemistry: Serves as a photoreactive handle for modifying surfaces, nanoparticles, or polymers in bioconjugation strategies.
• Materials Science Research: Employed in the surface functionalization of materials and the development of light-responsive or "smart" polymeric systems.
• Synthetic Intermediate: Acts as a precursor for synthesizing other diazirine-containing compounds and complex molecular architectures.

Basic Information

Product Name	3H-Diazirine-3,3-Dicarboxylic Acid Dipotassium Salt
CAS No.	76429-97-5
Molecular Formula	C4H2K2N2O4
Molecular Weight	220.27 g/mol
Synonyms	Dipotassium 3H-diazirine-3,3-dicarboxylate; Diazirine-3,3-dicarboxylic acid dipotassium salt; 3,3-Dicarboxy-3H-diazirine dipotassium salt; Dipotassium diazirinedicarboxylate; Photoaffinity labeling reagent; PAL reagent; Carbene precursor
EINECS	Contact for details

Quality Control

Our 3H-Diazirine-3,3-Dicarboxylic Acid Dipotassium Salt is produced and handled under strict quality protocols to ensure batch-to-batch consistency and reliability for sensitive research applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0%
Potassium Content	Conforms to theoretical

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.