Description

8-Benzyl-3α-Amino-1αh,5αh-Nortropane is a specialized nortropane alkaloid derivative, serving as a critical advanced intermediate in pharmaceutical research and development. Its value lies in its complex, functionalized structure, which provides a versatile scaffold for synthesizing novel bioactive compounds targeting the central nervous system. This high-purity building block is essential for medicinal chemists and R&D teams in the pharmaceutical and biotechnology sectors, particularly those focused on developing new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of potential drug candidates, especially those with tropane-related structures.
• Medicinal Chemistry Research: Used as a core scaffold for structure-activity relationship (SAR) studies and library synthesis in drug discovery programs.
• Neuroscience Research: Employed in the development of ligands and probes for studying neurotransmitter systems, including those involving dopamine and serotonin transporters.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in analytical laboratories.
• Process Chemistry: Utilized in route scouting and optimization for the scalable production of complex active pharmaceutical ingredients (APIs).

Basic Information

Product Name	8-Benzyl-3α-Amino-1αh,5αh-Nortropane
CAS No.	76272-35-0
Molecular Formula	C₁₅H₂₀N₂
Molecular Weight	228.34 g/mol
Synonyms	8-Benzyl-3α-amino-1αH,5αH-nortropane; 3α-Amino-8-benzyl-1αH,5αH-nortropane; 1αH,5αH-Nortropan-3α-amine, 8-benzyl-; Nortropane, 8-benzyl-3α-amino-1αH,5αH-; 76272-35-0; 8-Benzyl-3α-aminonortropane
EINECS	Contact for details

Quality Control

Our 8-Benzyl-3α-Amino-1αh,5αh-Nortropane is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via IR and NMR spectroscopy, to ensure it meets the high standards required for research and development. A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.