Description

1,2,3,4-Tetrahydro-8-[2-Hydroxy-3-(Isopropylamino)Propoxy]-1-(3-Pyridylcarbonyl)Quinoline is a high-purity synthetic intermediate of significant interest in advanced pharmaceutical research and development. Its complex molecular architecture makes it a valuable building block for the synthesis of novel therapeutic agents, particularly those targeting neurological and cardiovascular pathways. This compound is essential for R&D chemists and process development scientists in the pharmaceutical and biotechnology industries seeking to develop new active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of complex drug candidates and novel chemical entities.
• Neurological Research: Used in the development of compounds targeting neurotransmitter systems, potentially for conditions like Alzheimer's disease or Parkinson's disease.
• Cardiovascular Drug Development: Applied in research programs focused on creating new β-blocker or related cardiovascular agents due to its structural motifs.
• Chemical Biology Probe Synthesis: Utilized to create specialized molecules for studying protein-ligand interactions and cellular signaling pathways.
• Process Chemistry & Scale-Up: Employed in optimizing synthetic routes from laboratory scale to potential pilot-scale production for new APIs.
• Reference Standard: Acts as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.

Basic Information

Product Name	1,2,3,4-Tetrahydro-8-[2-Hydroxy-3-(Isopropylamino)Propoxy]-1-(3-Pyridylcarbonyl)Quinoline
CAS No.	76252-06-7
Molecular Formula	C23H29N3O3
Molecular Weight	395.50 g/mol
Synonyms	8-[2-Hydroxy-3-(isopropylamino)propoxy]-1,2,3,4-tetrahydro-1-(3-pyridinylcarbonyl)quinoline; 1-(3-Pyridinecarbonyl)-8-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]-1,2,3,4-tetrahydroquinoline; Quinoline derivative CAS 76252-06-7; THIQ derivative; 76252-06-7
EINECS	Contact for details

Quality Control

Every batch of 1,2,3,4-Tetrahydro-8-[2-Hydroxy-3-(Isopropylamino)Propoxy]-1-(3-Pyridylcarbonyl)Quinoline is manufactured under strict quality management systems. We provide comprehensive analytical documentation, including a Certificate of Analysis (COA) detailing purity, identity, and impurity profiles as determined by advanced techniques like HPLC, GC, and NMR. Our quality commitment ensures the material meets the stringent requirements for pharmaceutical R&D and other critical applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to exclude moisture. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.