Description

6-Bromo-2,3-dihydroquinolin-4(1H)-one is a versatile brominated heterocyclic building block of significant interest in advanced organic synthesis. Its core quinolinone scaffold, functionalized with a reactive bromine atom, makes it a critical intermediate for constructing complex molecular architectures. This compound is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and oncology.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its heterocyclic structure for bioactivity.
• Material Science: Acts as a building block for organic semiconductors, ligands for catalysts, and advanced polymers due to its electron-rich aromatic system.
• Chemical Synthesis: The bromine atom provides a handle for further functionalization via cross-coupling reactions (e.g., Suzuki, Heck) to create diverse chemical libraries.
• Academic & Contract Research: Essential for medicinal chemistry programs and methodological studies in universities and CROs (Contract Research Organizations).

Basic Information

Product Name	6-Bromo-2,3-dihydroquinolin-4(1H)-one
CAS No.	76228-06-3
Molecular Formula	C9H8BrNO
Molecular Weight	226.07 g/mol
Synonyms	6-Bromo-1,2,3,4-tetrahydro-4-oxoquinoline; 6-Bromo-1,2,3,4-tetrahydroquinolin-4-one; 6-Bromo-4-hydroxy-1,2,3,4-tetrahydroquinoline; 4(1H)-Quinolinone, 6-bromo-2,3-dihydro-; 6-Bromotetrahydro-4-quinolone
EINECS	Contact for details

Quality Control

Our production of 6-Bromo-2,3-dihydroquinolin-4(1H)-one adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide a detailed Certificate of Analysis (COA) with each shipment, ensuring traceability and compliance with your research or production standards. Our facilities operate under cGMP principles where applicable to guarantee consistency and reliability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.