Description

Heparin Derived Disaccharide Mw600 Da is a well-defined, low molecular weight oligosaccharide fragment obtained from the controlled depolymerization of heparin. This compound is crucial for research and development in the life sciences, serving as a key reference standard and building block. It is primarily needed by pharmaceutical R&D teams, diagnostic manufacturers, and academic researchers working on anticoagulant mechanisms, glycobiology, and the development of novel heparin-based therapeutics.

Application

• Pharmaceutical Reference Standard: Used as a critical calibrant and control in the quality assurance and analytical testing of low molecular weight heparins (LMWHs) and related products.
• Biochemical Research: Serves as a precise tool for studying heparin-protein interactions, enzyme kinetics (e.g., with heparinases), and structure-activity relationships (SAR) in anticoagulant pathways.
• Diagnostic Reagent Development: Employed in the formulation and calibration of diagnostic kits and assays designed to measure heparin activity or related biomarkers in clinical samples.
• Glycobiology & Drug Discovery: Acts as a defined substrate or inhibitor in screens for novel enzymes or therapeutic agents targeting the heparan sulfate proteoglycan system.
• Production of Ultra-Low Molecular Weight Heparins (ULMWH): Can be used as a starting material or intermediate in the synthesis of next-generation, more uniform anticoagulant drugs.

Basic Information

Product Name	Heparin Derived Disaccharide Mw600 Da
CAS No.	76149-63-8
Molecular Formula	Typically C12H19NO14S2 (for a common δUA-GlcNS,6S structure) - Contact for details
Molecular Weight	~600 Da (Average)
Synonyms	Heparin Disaccharide I-S; Heparin Disaccharide II-S; δUA-GlcNS,6S; δUA2S-GlcNS,6S (Isomer specific); Low Molecular Weight Heparin Fragment; Heparin Oligosaccharide; Heparin-derived Diaccharide; LMWH Disaccharide
EINECS	Contact for details

Quality Control

Our Heparin Derived Disaccharide is produced and tested under a strict quality management system. Each batch is characterized using advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure structural identity and purity. Certificates of Analysis (COA) detailing batch-specific results are available upon request, supporting compliance with research and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a freezer at -20°C or below for long-term stability. This material is hygroscopic (moisture-sensitive); allow the sealed container to equilibrate to room temperature before opening to prevent condensation and moisture uptake.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 5.0 %
Specific Optical Rotation	Contact for details
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.