Description

7-Fluoroquinazoline-2,4(1H,3H)-Dione is a high-purity fluorinated heterocyclic building block of significant interest in advanced organic synthesis. This compound matters as a key intermediate for developing novel pharmaceuticals and agrochemicals, where the introduction of a fluorine atom can dramatically alter biological activity and metabolic stability. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing complex quinazoline-based molecules.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of kinase inhibitors, anticancer agents, and other biologically active quinazoline derivatives.
• Agrochemical Research: Used in the development of new herbicides and fungicides, leveraging the fluorine atom for enhanced efficacy and environmental profile.
• Chemical Biology Probe Synthesis: Serves as a scaffold for creating fluorescent tags or activity-based probes to study enzyme function and biological pathways.
• Material Science Precursor: Potential building block for organic electronic materials or metal-organic frameworks (MOFs) due to its rigid, heteroaromatic structure.
• Academic & Contract Research: Essential for methodological studies in fluorination chemistry and heterocycle construction within university and CRO laboratories.

Basic Information

Product Name	7-Fluoroquinazoline-2,4(1H,3H)-Dione
CAS No.	76088-98-7
Molecular Formula	C8H5FN2O2
Molecular Weight	180.14 g/mol
Synonyms	7-Fluoro-1H,3H-quinazoline-2,4-dione; 7-Fluoro-2,4-dihydroxyquinazoline; 7-Fluoroquinazoline-2,4-diol; 2,4-Dihydroxy-7-fluoroquinazoline; 7-Fluoro-2,4(1H,3H)-quinazolinedione; 7-Fluoro-1H-quinazoline-2,4-dione
EINECS	Contact for details

Quality Control

Our 7-Fluoroquinazoline-2,4(1H,3H)-Dione is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). The compound should be kept under an inert atmosphere for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.