Description

7-α-Hydroxy-cis-Oxabicyclo[3.3.0]Octane-3-One is a high-purity, advanced pharmaceutical intermediate characterized by its unique oxabicyclo[3.3.0]octane core structure. This compound is critical for the synthesis of complex bioactive molecules, particularly in the development of prostaglandin analogs and other specialized therapeutics. It is an essential building block for research and production teams in the pharmaceutical, biotechnology, and fine chemical sectors seeking to develop novel drug candidates with high stereochemical purity.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the multi-step synthesis of prostaglandin derivatives and related therapeutic agents.
• Biochemical Research: Used as a precursor in academic and industrial research for studying enzyme interactions and metabolic pathways.
• Fine Chemical Synthesis: Serves as a versatile starting material for constructing complex, stereochemically defined molecular architectures.
• Process Development: Employed in scaling up and optimizing synthetic routes for new chemical entities (NCEs) in pilot plants and commercial manufacturing.

Basic Information

Product Name	7-α-Hydroxy-cis-Oxabicyclo[3.3.0]Octane-3-One
CAS No.	76023-85-3
Molecular Formula	C7H10O3
Molecular Weight	142.15 g/mol
Synonyms	(7α)-7-Hydroxy-2,8-dioxatricyclo[3.3.0.03,7]octan-4-one; 7α-Hydroxy-2,8-dioxatricyclo[3.3.0.0³,⁷]octan-4-one; 7α-Hydroxy-cis-oxabicyclo[3.3.0]octane-3-one; 7α-Hydroxy-3-oxa-cis-bicyclo[3.3.0]octan-2-one; Prostaglandin Intermediate; PG Intermediate
EINECS	Contact for details

Quality Control

Our 7-α-Hydroxy-cis-Oxabicyclo[3.3.0]Octane-3-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and chiral analysis, to ensure it meets the stringent requirements for pharmaceutical intermediate use. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming identity, purity, and conformance to agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) in the original sealed container to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Chiral Purity	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.