Description

Iofetamine is a specialized radiopharmaceutical precursor, a critical component in the synthesis of diagnostic imaging agents. Its primary value lies in enabling the production of I-123 labeled compounds used in Single Photon Emission Computed Tomography (SPECT) for neurological assessments. This compound is essential for manufacturers and research institutions developing radiopharmaceuticals for brain perfusion imaging, particularly in the evaluation of conditions like dementia and stroke.

Application

• Radiopharmaceutical Synthesis: Primary precursor for the production of I-123 iofetamine (IMP), a brain perfusion imaging agent.
• SPECT Imaging Agent Development: Key starting material in the research and manufacturing of technetium-99m and iodine-123 based diagnostic tracers.
• Neurological Disorder Diagnostics: Used in the creation of compounds for assessing cerebral blood flow in conditions such as Alzheimer's disease, epilepsy, and cerebrovascular disease.
• Nuclear Medicine Research: Vital for academic and industrial R&D focused on advancing neuroimaging techniques and novel radiopharmaceuticals.
• Pharmaceutical Intermediate: Serves as a high-purity chemical intermediate in controlled synthesis processes under GMP conditions.

Basic Information

Product Name	Iofetamine
CAS No.	75917-92-9
Molecular Formula	C12H18IN
Molecular Weight	303.18 g/mol
Synonyms	N-Isopropyl-4-iodoamphetamine; IMP; Iofetamine Hydrochloride; N-Isopropyl-p-iodoamphetamine; (4-Iodophenyl)-1-methyl-2-propylamine; 1-(4-Iodophenyl)-N-isopropylpropan-2-amine; p-Iodo-N-isopropylamphetamine; HIPDM (historically for hydroxy analog)
EINECS	Contact for details

Quality Control

Our Iofetamine is manufactured and tested to meet the stringent requirements for pharmaceutical intermediates and active substance starting materials. Quality assurance includes rigorous analytical controls for identity, purity, and impurity profiles. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing results from tests such as HPLC assay, related substances, residual solvents, and specific identification. Production can be aligned with GMP guidelines for radiopharmaceutical precursor applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its light-sensitive nature, the container should be opaque or kept in secondary light-protective packaging. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.