Description

7-Chloro-3-Dimethylamino-2,4-Dioxo-1H-Quinazoline-6-Sulfonamide is a high-purity, specialized heterocyclic sulfonamide compound that serves as a critical synthetic intermediate. Its value lies in its unique molecular scaffold, which is essential for constructing more complex pharmacologically active molecules. This product is primarily needed by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly in medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of potential drug candidates, particularly those targeting enzymatic pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• Process Development: Serves as a reference standard or starting material for scaling up synthetic routes under Good Manufacturing Practice (GMP) conditions.
• Biochemical Tool Compound: May be utilized in vitro to study biological interactions and mechanisms of action.
• Custom Synthesis: A foundational substrate for contract research organizations (CROs) and CDMOs producing bespoke molecules for clients.

Basic Information

Product Name	7-Chloro-3-Dimethylamino-2,4-Dioxo-1H-Quinazoline-6-Sulfonamide
CAS No.	75787-40-5
Molecular Formula	C10H9ClN4O4S
Molecular Weight	316.72 g/mol
Synonyms	7-Chloro-3-(dimethylamino)-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamide; 7-Chloro-3-dimethylamino-2,4(1H,3H)-quinazolinedione-6-sulfonamide; 6-Sulfamoyl-7-chloro-3-(dimethylamino)-1H-quinazoline-2,4-dione; 7-Chloro-3-(N,N-dimethylamino)-2,4-dioxo-1,2,3,4-tetrahydroquinazoline-6-sulfonamide; Quinazoline-6-sulfonamide, 7-chloro-3-(dimethylamino)-1,2,3,4-tetrahydro-2,4-dioxo-; CAS 75787-40-5
EINECS	Contact for details

Quality Control

Our 7-Chloro-3-Dimethylamino-2,4-Dioxo-1H-Quinazoline-6-Sulfonamide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product is light-sensitive (store away from light) and may be hygroscopic (moisture-sensitive); therefore, containers should be kept sealed under inert atmosphere when not in use to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.