Description

1-Cyclopropyl-2,2,2-Trifluoroethan-1-Amine Hydrochloride is a high-purity, synthetically valuable chiral amine building block. This compound is critical for the development of novel active pharmaceutical ingredients (APIs) and advanced agrochemicals, where its cyclopropyl and trifluoromethyl groups impart unique steric and electronic properties. It is primarily utilized by research and development chemists, process development teams, and manufacturers in the pharmaceutical and agrochemical industries seeking to introduce specific structural motifs into their target molecules.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of potential drug candidates, particularly in central nervous system (CNS) and antiviral therapeutic areas.
• Agrochemical Research: Used as a building block for developing novel herbicides, fungicides, and insecticides with enhanced efficacy and environmental profile.
• Ligand and Catalyst Development: Serves as a precursor for chiral ligands used in asymmetric synthesis and catalysis.
• Material Science Research: Employed in the synthesis of specialty polymers and advanced materials requiring fluorinated components.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Academic & Industrial R&D: Used in research laboratories for methodological studies and exploring new chemical spaces.

Basic Information

Product Name	1-Cyclopropyl-2,2,2-Trifluoroethan-1-Amine Hydrochloride
CAS No.	75702-99-7
Molecular Formula	C5H9ClF3N
Molecular Weight	175.58 g/mol
Synonyms	1-Cyclopropyl-2,2,2-trifluoroethylamine hydrochloride; α-(Cyclopropyl)-2,2,2-trifluoroethylamine hydrochloride; (1-Cyclopropyl-2,2,2-trifluoroethyl)amine hydrochloride; 2,2,2-Trifluoro-1-cyclopropylethanamine hydrochloride; 1-Amino-2,2,2-trifluoro-1-cyclopropylethane hydrochloride; (R/S)-1-Cyclopropyl-2,2,2-trifluoroethanamine hydrochloride; Trifluoro(cyclopropyl)methylamine hydrochloride
EINECS	Contact for details

Quality Control

Our 1-Cyclopropyl-2,2,2-Trifluoroethan-1-Amine Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including chiral purity determination, to ensure it meets the stringent requirements for advanced synthetic applications. A detailed Certificate of Analysis (COA) providing full specification data is supplied with every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect product stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee (or as specified)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.