Description

(R)-3,3'-Dibromo-2,2'-Dimethoxy-1,1'-Binaphthyl CAS NO 75640-69-6 is a high-value, enantiomerically pure binaphthyl derivative that serves as a critical chiral building block and ligand precursor in advanced organic synthesis. Its core value lies in its ability to induce and control stereochemistry, which is paramount for developing pharmaceuticals and functional materials with specific optical activity. This compound is essential for research and production teams in the pharmaceutical, agrochemical, and specialty chemical industries who require high-purity chiral intermediates for asymmetric catalysis and molecular recognition.

Application

• Chiral Ligand Synthesis: A key precursor for synthesizing sophisticated chiral phosphine and N-heterocyclic carbene (NHC) ligands used in asymmetric hydrogenation and cross-coupling reactions.
• Pharmaceutical Intermediate: Employed in the research and development of enantiomerically pure active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and cardiovascular drugs.
• Asymmetric Catalyst Preparation: Used to construct chiral catalysts for enantioselective synthesis, improving the efficiency and selectivity of manufacturing processes.
• Material Science Research: Serves as a building block for chiral organic frameworks, liquid crystals, and polymers with novel optical or electronic properties.
• Agrochemical Development: Applied in creating chiral pesticides and herbicides where the specific stereoisomer is crucial for biological activity and environmental safety.
• Academic & Process Chemistry: A valuable tool for method development and mechanistic studies in university and industrial R&D laboratories focused on stereochemistry.

Basic Information

Product Name	(R)-3,3'-Dibromo-2,2'-Dimethoxy-1,1'-Binaphthyl
CAS No.	75640-69-6
Molecular Formula	C₂₂H₁₆Br₂O₂
Molecular Weight	472.17 g/mol
Synonyms	(R)-3,3'-Dibromo-2,2'-dimethoxy-1,1'-binaphthalene; (R)-3,3'-Dibromo-2,2'-dimethoxybinaphthyl; (R)-3,3'-Dibromo-2,2'-dimethoxy-[1,1'-binaphthalene]; (R)-BINOL-3,3'-dibromo-2,2'-dimethyl ether; (R)-3,3'-Dibromo-2,2'-dimethoxy-1,1'-binaphthyl; (R)-3,3'-Dibromo-2,2'-dimethoxy-[1,1']binaphthalenyl; (R)-3,3'-Dibromobinaphthol dimethyl ether
EINECS	Contact for details

Quality Control

Our (R)-3,3'-Dibromo-2,2'-Dimethoxy-1,1'-Binaphthyl is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC for enantiomeric excess (ee) verification, to ensure high chemical and optical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Melting Point	Contact for details
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.