Description

8-Methoxy-5,6,7,8-Tetrahydroquinoline is a versatile heterocyclic building block and key synthetic intermediate of significant interest in advanced organic synthesis. Its partially hydrogenated quinoline core, functionalized with a methoxy group, makes it a valuable precursor for pharmaceuticals, agrochemicals, and specialty materials. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A crucial building block in the synthesis of active pharmaceutical ingredients (APIs), particularly for compounds targeting the central nervous system or possessing complex polycyclic structures.
• Agrochemical Synthesis: Serves as a precursor in the development of novel herbicides, fungicides, and insecticides, leveraging its heterocyclic scaffold.
• Ligand and Catalyst Development: Used to create novel nitrogen-containing ligands for transition metal catalysis in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of organic semiconductors, light-emitting materials, and other functional organic compounds due to its electron-donating methoxy group and aromatic system.
• Dye and Pigment Intermediate: Acts as a starting material for the synthesis of specialized quinoline-based dyes and colorants.
• Academic and R&D Laboratories: Used extensively in methodological research and for exploring new synthetic pathways in organic chemistry.

Basic Information

Product Name	8-Methoxy-5,6,7,8-Tetrahydroquinoline
CAS No.	75414-07-2
Molecular Formula	C₁₀H₁₃NO
Molecular Weight	163.22 g/mol
Synonyms	8-Methoxy-5,6,7,8-tetrahydroquinoline; 5,6,7,8-Tetrahydro-8-methoxyquinoline; 8-Methoxy-1,2,3,4-tetrahydroquinoline; 8-Methoxy-THQ; Tetrahydro-8-methoxyquinoline
EINECS	Contact for details

Quality Control

Our 8-Methoxy-5,6,7,8-Tetrahydroquinoline is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with every shipment, documenting all critical quality attributes. Our commitment to quality supports applications from research to scale-up under cGMP guidelines where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.