Description

8-(Trifluoromethyl)-1,2,3,4-Tetrahydroquinoline is a high-value, fluorinated heterocyclic building block essential for advanced chemical synthesis. This compound is prized for its ability to introduce the metabolically stable and lipophilic trifluoromethyl group into complex molecular architectures. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical industries for the creation of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon for the development of new drug candidates, particularly in central nervous system (CNS) and oncology research.
• Agrochemical Synthesis: Used in the production of advanced herbicides, fungicides, and insecticides, where the CF₃ group enhances biological activity and environmental stability.
• Material Science Precursor: Serves as a building block for specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: Employed in academic and industrial R&D for methodology development and the synthesis of complex fluorinated molecules.
• Ligand and Catalyst Design: Utilized to create novel nitrogen-containing ligands for catalytic systems in asymmetric synthesis.

Basic Information

Product Name	8-(Trifluoromethyl)-1,2,3,4-Tetrahydroquinoline
CAS No.	75414-01-6
Molecular Formula	C₁₀H₁₀F₃N
Molecular Weight	201.19 g/mol
Synonyms	8-(Trifluoromethyl)-1,2,3,4-tetrahydroquinoline; 1,2,3,4-Tetrahydro-8-(trifluoromethyl)quinoline; 8-Trifluoromethyl-1,2,3,4-tetrahydroquinoline; Quinoline, 1,2,3,4-tetrahydro-8-(trifluoromethyl)-; 8-CF3-Tetrahydroquinoline
EINECS	Contact for details

Quality Control

Our 8-(Trifluoromethyl)-1,2,3,4-Tetrahydroquinoline is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide detailed Certificates of Analysis (COA) with each shipment, confirming compliance with customer specifications and industry best practices.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.