Description

(+/-)-2-Hydroxy-2-Phenylpropionic Acid Hemihydrate CAS NO 75378-83-5 is a chiral α-hydroxy acid derivative, serving as a versatile intermediate in fine chemical synthesis. Its value lies in its ability to act as a key building block for pharmaceuticals, agrochemicals, and advanced materials, enabling the introduction of a phenyl-substituted lactic acid moiety. This compound is essential for research and development chemists, process engineers, and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries.

Application

• Pharmaceutical Intermediate: A crucial chiral precursor in the synthesis of non-steroidal anti-inflammatory drugs (NSAIDs), analgesics, and other active pharmaceutical ingredients (APIs).
• Agrochemical Synthesis: Used in the production of herbicides and plant growth regulators, leveraging its acidic and complexing properties.
• Catalyst and Ligand Preparation: Serves as a starting material for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Polymer Modification: Acts as a monomer or modifying agent for creating specialty polymers with enhanced properties.
• Cosmetic and Personal Care Ingredients: A potential intermediate for synthesizing skin-conditioning agents and mild exfoliants.
• Chemical Research: Employed in academic and industrial R&D for method development and exploring new synthetic pathways.

Basic Information

Product Name	(+/-)-2-Hydroxy-2-Phenylpropionic Acid Hemihydrate
CAS No.	75378-83-5
Molecular Formula	C9H10O3 • ½H2O
Molecular Weight	169.16 g/mol (anhydrous basis)
Synonyms	DL-2-Hydroxy-2-phenylpropionic acid hemihydrate; (±)-2-Hydroxy-2-phenylpropanoic acid hemihydrate; 2-Phenyl-2-hydroxypropionic acid hemihydrate; DL-Atrolactic acid hemihydrate; (±)-Atrolactic acid hemihydrate; α-Hydroxy-α-methylbenzeneacetic acid hemihydrate; 2-Hydroxy-2-methyl-2-phenylacetic acid hemihydrate
EINECS	Contact for details

Quality Control

Our (+/-)-2-Hydroxy-2-Phenylpropionic Acid Hemihydrate is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets precise specifications for research and industrial use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is available for every shipment upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent absorption of atmospheric moisture, which can affect product quality and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	4.0% - 6.0% (Theoretical for hemihydrate: ~5.1%)
Melting Point	Approx. 90 - 95 °C
Heavy Metals	< 20 ppm
Residue on Ignition	< 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.