Description

Ethyl 4-(3-Nitrophenyl)-4-Oxobutyrate is a high-purity organic ester derivative featuring a nitro-substituted aromatic ketone moiety. This compound serves as a versatile and critical chemical intermediate in advanced organic synthesis, enabling the production of complex molecules. It is primarily required by pharmaceutical and agrochemical research and development teams for constructing active pharmaceutical ingredients (APIs) and novel crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug molecules and active pharmaceutical ingredients (APIs), particularly those requiring a nitrophenyl ketone ester scaffold.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where its structure contributes to biological activity.
• Organic Synthesis & Research: Serves as a versatile precursor for further chemical transformations, including reduction, hydrolysis, and condensation reactions in academic and industrial R&D laboratories.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, dyes, and functional materials that incorporate aromatic ketone esters.
• Chemical Reference Standard: Supplied in high-purity grades for use as an analytical standard in quality control and method development.

Basic Information

Product Name	Ethyl 4-(3-Nitrophenyl)-4-Oxobutyrate
CAS No.	75227-18-8
Molecular Formula	C12H13NO5
Molecular Weight	251.24 g/mol
Synonyms	Ethyl 4-(3-Nitrophenyl)-4-oxobutanoate; 4-(3-Nitrophenyl)-4-oxobutanoic Acid Ethyl Ester; 3-Nitrobenzoylacetic Acid Ethyl Ester; Ethyl 3-Nitrobenzoylacetate; Butanoic acid, 4-(3-nitrophenyl)-4-oxo-, ethyl ester; Ethyl (3-nitrobenzoyl)acetate; Ethyl 4-oxo-4-(3-nitrophenyl)butyrate
EINECS	Contact for details

Quality Control

Our Ethyl 4-(3-Nitrophenyl)-4-Oxobutyrate is manufactured under a strict quality management system. Each batch undergoes rigorous analytical testing, including HPLC for purity and IR for structural confirmation, to ensure it meets exacting specifications for use as a synthesis intermediate. Certificates of Analysis (COA) documenting identity, purity, and impurity profiles are available for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. This material is light-sensitive; prolonged exposure to light should be avoided.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder or solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.