Description

1H-Isoindole-1,3(2H)-Dione, 2-((4-Oxo-3(4H)-Quinazolinyl)Methyl)-, Dihydrochloride is a high-purity, pharmaceutically relevant chemical intermediate. This compound is valued for its role as a key building block in the synthesis of complex molecules, particularly in medicinal chemistry research and development. It is primarily sought after by pharmaceutical R&D laboratories and fine chemical manufacturers for the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs) and drug candidates, particularly those targeting specific enzyme pathways.
• Medicinal Chemistry Research: Used as a core scaffold or building block for structure-activity relationship (SAR) studies and the development of new chemical entities in drug discovery programs.
• Organic Synthesis: Serves as a versatile reagent for constructing complex heterocyclic systems containing isoindole and quinazolinone moieties.
• Biochemical Research: Potential use as a tool compound or inhibitor in biochemical assays to study biological mechanisms.
• Fine Chemical Production: Employed in the multi-step synthesis of specialty chemicals and advanced materials requiring high structural precision.

Basic Information

Product Name	1H-Isoindole-1,3(2H)-Dione, 2-((4-Oxo-3(4H)-Quinazolinyl)Methyl)-, Dihydrochloride
CAS No.	75159-42-1
Molecular Formula	C₁₇H₁₂N₃O₃·2HCl
Molecular Weight	379.21 g/mol (free base: 306.30 g/mol)
Synonyms	2-((4-Oxo-3,4-dihydroquinazolin-3-yl)methyl)isoindoline-1,3-dione dihydrochloride; 3-(1,3-Dioxoisoindolin-2-yl)methyl)-3,4-dihydroquinazolin-4-one dihydrochloride; Quinazolinone-isoindoledione derivative dihydrochloride; N-(4-Oxo-3,4-dihydroquinazolin-3-ylmethyl)phthalimide dihydrochloride; Phthalimide-quinazolinone conjugate dihydrochloride
EINECS	Contact for details

Quality Control

Our 1H-Isoindole-1,3(2H)-Dione, 2-((4-Oxo-3(4H)-Quinazolinyl)Methyl)-, Dihydrochloride is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after each use to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.