Description

Diethyl 2-[[(4-Oxoquinazolin-3-Yl)Methylamino]Methyl]Propanedioate Dihydrochloride is a high-purity, dihydrochloride salt derivative of a functionalized quinazolinone, designed for advanced research and pharmaceutical development. This compound is valued for its role as a key synthetic intermediate or a potential active pharmaceutical ingredient (API) precursor in medicinal chemistry. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and fine chemical sectors for developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of complex drug molecules, particularly those targeting kinase inhibition or other biological pathways.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies for the discovery of new bioactive compounds.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.
• Biochemical Probe: Utilized in biochemical assays to study enzyme function and cellular signaling mechanisms.
• Fine Chemical Synthesis: Acts as a specialized intermediate for the custom synthesis of complex organic molecules in contract research and manufacturing (CRAM) organizations.

Basic Information

Product Name	Diethyl 2-[[(4-Oxoquinazolin-3-Yl)Methylamino]Methyl]Propanedioate Dihydrochloride
CAS No.	75159-23-8
Molecular Formula	C₁₇H₂₂Cl₂N₄O₅
Molecular Weight	433.29 g/mol
Synonyms	Diethyl 2-(((4-oxo-3(4H)-quinazolinyl)methylamino)methyl)propanedioate dihydrochloride; Propanedioic acid, 2-[[(4-oxo-3(4H)-quinazolinyl)methylamino]methyl]-, 1,3-diethyl ester, dihydrochloride; 3-(((Diethoxycarbonyl)methyl)(methyl)amino)methyl)quinazolin-4(3H)-one dihydrochloride; 75159-23-8; Quinazolinone derivative dihydrochloride salt
EINECS	Contact for details

Quality Control

Our Diethyl 2-[[(4-Oxoquinazolin-3-Yl)Methylamino]Methyl]Propanedioate Dihydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and tests for residual solvents and moisture content. We provide a detailed Certificate of Analysis (COA) with every shipment to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines
Heavy Metals	< 20 ppm
Chloride Content	Conforms to theoretical value

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.