Description

7,8,9,10-Tetrahydrobenzo[A]Pyrene-7,8,9,10-Tetrol is a high-purity polycyclic aromatic hydrocarbon (PAH) derivative, specifically a tetrol metabolite of benzo[a]pyrene. This compound is of significant value in advanced research and analytical chemistry due to its role as a critical reference standard and a key intermediate in metabolic and toxicological studies. It is primarily required by pharmaceutical R&D laboratories, environmental testing facilities, and academic institutions focused on carcinogenesis, biomarker discovery, and analytical method development.

Application

• Biomarker and Metabolite Research: Serves as a crucial reference standard for the identification and quantification of benzo[a]pyrene metabolites in biological samples.
• Toxicology and Carcinogenicity Studies: Used as a precise analytical standard to study the metabolic activation pathways and DNA adduct formation of PAHs.
• Environmental Analysis: Employed in calibrating sophisticated analytical instruments (e.g., HPLC-MS, GC-MS) for monitoring PAH pollution and human exposure.
• Pharmaceutical Development: Acts as a key intermediate or reference compound in the research of detoxification enzymes and chemopreventive agents.
• Quality Control and Assurance: Essential for laboratories requiring certified reference materials (CRMs) to validate analytical methods and ensure regulatory compliance.
• Academic and Institutional Research: Supports fundamental studies in organic chemistry, biochemistry, and environmental health sciences.

Basic Information

Product Name	7,8,9,10-Tetrahydrobenzo[A]Pyrene-7,8,9,10-Tetrol
CAS No.	75110-14-4
Molecular Formula	C₂₀H₁₆O₄
Molecular Weight	320.34 g/mol
Synonyms	Benzo[a]pyrene-7,8,9,10-tetrol; 7,8,9,10-Tetrahydroxy-7,8,9,10-tetrahydrobenzo[a]pyrene; BP-7,8,9,10-tetrol; (±)-anti-BPDE tetrol; r-7,t-8,9,c-10-Tetrahydroxy-7,8,9,10-tetrahydrobenzo[a]pyrene; Benzo[a]pyrene 7,8,9,10-tetrahydrotetrol; B[a]P-7,8,9,10-tetrol
EINECS	Contact for details

Quality Control

Our 7,8,9,10-Tetrahydrobenzo[A]Pyrene-7,8,9,10-Tetrol is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and analytical applications. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment to guarantee traceability and consistency for your critical work.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) to prevent oxidation. For long-term storage, keep the material desiccated to maintain stability. Allow the sealed container to reach room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95% (Area %)
Assay	≥ 90% (by HPLC)
Water Content	≤ 1.0% (KF)
Residual Solvents	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.